Treatment supporting efficacy

Breast cancer (BrCa) is a predominant malignancy, with metastasis occurring in one in eight patients, nearly half of which target the bone, leading to serious complications such as pain, fractures, and compromised mobility. This study aims to assess the efficacy of CTRA in monitoring osteolytic lesions’ progression and response to therapy, suggesting its potential superiority over existing methodologies in guiding treatment strategies.

13p vishanshan 27-06-2024 1 1   Download

Nutritional support, including nutritional counseling and oral nutritional supplements (ONS), has been recommended as a first-line strategy in patients with non-small cell lung cancer (NSCLC). Evidence on the efficacy of immunonutrition during immunotherapy in these patients is positive, but still limited some secondary endpoints, such as treatment toxicity and tolerance.

10p vileonardodavinci 23-12-2023 4 2   Download

Prehabilitation and recovery programmes aim to optimise patients’ physical fitness and mental wellbeing before, during and after cancer treatment. This paper aimed to understand the impact of such a programme on emotional well-being in individuals undergoing cancer surgery. The programme was multi-modal, containing physical activity, well-being and nutritional support.

10p vileonardodavinci 23-12-2023 5 2   Download

Part 1 book "Hospice and palliative care for companion animals - Principles and practice" includes content: Introduction, what is animal hospice and palliative care; the interdisciplinary team; quality of life assessments; recognizing distress; balancing efficacy of treatments against burdens of care; ethical decision making in animal hospice and palliative care; supportive relationships - veterinarians and animal hospice providers’ nonmedical roles; management and administration - business models,... and other contents.

218p muasambanhan01 13-12-2023 5 4   Download

In this article, we report two cases of comprehensive treatment with clear aligner from Invisalign within 18 months, under the support of artificial intelligence to plan tooth movement through Clincheck© software. The aim is to present the efficacy of the latest orthodontic therapy, and to offer patients more treatment options in correcting various types of malocclusion.

6p vischultz 17-10-2023 2 2   Download

Cesium is an inorganic compound, which is not approved by the Food and Drug Administration (FDA), and is available as over-the-counter (OTC) drug. Despite lack of supportive data on efficacy, and evidence of safety of the cesium, this drug is used by the patients for treatment of cancer depression and other conditions.

3p viintuit 26-09-2023 1 0   Download

Silica supports used e.g. in chromatography, separation and bioassay lack complete efficacy unless they are surface functionalised. Thus, chemistries are grafted to the surface to enhance their properties and capacity in specific applications.

9p vironald 15-12-2022 7 2   Download

A nutritious diet is critical to minimizing disease progression of human immunodeficiency virus (HIV) and maximizing treatment efficacy. In low resource settings, meeting the food preference needs of people living with the HIV (PLHIV) can be achieved with a supportive food environment when HIV status is disclosed. However, less is known about family-level strategies related to building a supportive food environment.

12p viferrari 28-11-2022 6 2   Download

Current guidelines consider T-DM1 the standard 2nd line therapy for HER2 positive metastatic breast cancer (MBC) patients following trastuzumab (T)+pertuzumab (P) and taxane 1st line treatment. Despite this, there are no prospective studies supporting this sequence.

7p visusanwojcicki 28-06-2022 6 2   Download

Several reports have shown that postoperative monitoring of general safety and quality issues, including pain treatment, after discharge from recovery is often non-systematic and inadequate. We suggest a new score with assessment of key recovery parameters, as a supportive tool for postoperative care and a call-out algorithm for need of extra help. The aim of this investigation was to validate the score.

10p viottohahn 30-03-2022 10 1   Download

The purpose of the study described here was to evaluate the effects of different supportive treatments - such as antioxidants, immunomodulators, and nonsteroidal anti-inflammatory drugs (NSAIDs) - in mastitic cows treated with intramammary antibiotics on the efficacy of mastitis therapy and fertility indices.

10p vigalileogalilei 28-02-2022 11 1   Download

This paper provides an overview of systematic reviews that assessed the effectiveness of SOT compared with the best supportive care (BSC) or placebo in patients with advanced esophageal or gastric cancers in an end-of-life context.

18p vimahuateng 26-11-2021 7 1   Download

Surveyingrelated factors, clinical characteristics of herpes zoster thatareinpatient treated in the Department of AllergyDermatology, Central Military Hospital 108 from 6/2015- 6/2018. Determinatingchanges in humoral immunity (IgA, IgG and IgM) and cellular immunity (TCD3, TCD4, TCD8, CD19 and CD16+56) in blood of patients with herpes zoster before and after treatment.

27p kequaidan12 03-06-2021 25 4   Download

Recent studies have reported that radial extracorporeal shock wave therapy (rESWT) reduces pain and improves function in patients with mild to moderately severe carpal tunnel syndrome (CTS) compared to a placebo. However, most of those studies used multi-session rESWT combined with wrist support and evaluation of efficacy was limited to a maximum of 14 weeks.

9p vitennessee2711 02-02-2021 5 0   Download

Pharmacological treatment of complex diseases using more than two drugs is commonplace in the clinic due to better efficacy, decreased toxicity and reduced risk for developing resistance. However, many of these higher-order treatments have not undergone any detailed preceding in vitro evaluation that could support their therapeutic potential and reveal disease related insights.

20p vijisoo2711 27-10-2020 17 2   Download

Case management has been shown to be beneficial in phases of cancer screening and treatment. After treatment is completed, patients experience a loss of support due to reduced contact with medical professionals. Case management has the potential to offer continuity of care and ease re-entry to normal life. We therefore aim to investigate the effect of case management on quality of life in early cancer survivors.

8p vimale2711 21-08-2020 12 1   Download

Women with breast cancer undergoing chemotherapy suffer from a number of symptoms and report receiving inadequate support from health care professionals. Innovative and easily accessible interventions are lacking.

9p vithimphu2711 31-07-2020 10 2   Download

A trough concentration (Cmin) ≥20 μg/mL of teicoplanin is recommended for the treatment of serious methicillin-resistant Staphylococcus aureus (MRSA) infections. However, sufficient clinical evidence to support the efficacy of this target Cmin has not been obtained.

10p vidhaka2711 31-07-2020 24 1   Download

Nivolumab has changed the treatment of advanced gastric cancer (AGC). Nivolumab shows better outcomes compared to best supportive care among AGC patients who received at least two prior regimens.

6p vidhaka2711 31-07-2020 15 1   Download

Treatment with nab-paclitaxel plus gemcitabine increases survival in patients with metastatic pancreatic cancer. However, the assessment of treatment efficacy and safety in non-selected patients in a real-life setting may provide useful information to support decision-making processes in routine practice.

11p viputrajaya2711 22-06-2020 11 0   Download