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Báo cáo khoa học: A novel, promoter-based, target-specific assay identifies 2-deoxy-D-glucose as an inhibitor of globotriaosylceramide biosynthesis

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:12

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Abnormal biosynthesis of globotriaosylceramide (Gb3) is known to be associated with Gb3-related diseases, such as Fabry disease. The Gb3 synthase gene (Gb3S) codes for a1,4-galactosyltransferase, which is a key enzyme involved in Gb3 biosynthesisin vivo.

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Nội dung Text: Báo cáo khoa học: A novel, promoter-based, target-specific assay identifies 2-deoxy-D-glucose as an inhibitor of globotriaosylceramide biosynthesis

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