Báo cáo khoa học: Completing the hypusine pathway in Plasmodium Deoxyhypusine hydroxylase is an E-Z type HEAT repeat protein
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In searching for new targets for antimalarials we investigated the biosyn-thesis of hypusine present in eukaryotic initiation factor-5A (eIF-5A) in Plasmodium. Here, we describe the cloning and expression of deoxyhypu-sine hydroxylase (DOHH), which completes the modification of eIF-5A through hydroxylation of deoxyhypusine.
Chủ đề:
- scientific reports
- thesis report
- medical report
- In searching for new targets for antimalarials we investigated the biosyn-thesis of hypusine present in eukaryotic initiation factor-5A (eIF-5A) in Plasmodium. Here
- we describe the cloning and expression of deoxyhypu-sine hydroxylase (DOHH)
- which completes the modification of eIF-5A through hydroxylation of deoxyhypusine.
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