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Báo cáo khoa học: Increased expression of c-Fos by extracellular signal-regulated kinase activation under sustained oxidative stress elicits BimEL upregulation and hepatocyte apoptosis
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We previously reported that the inhibition of catalase and glutathione per-oxidase activities by treatment with 3-amino-1,2,4-triazole (ATZ) and mer-captosuccinic acid evoked sustained increases in the levels of reactive oxygen species and apoptosis in rat primary hepatocytes.
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