Báo cáo khoa học: The role of Tyr71 in Streptomyces trypsin on the recognition mechanism of structural protein substrates
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Studies of substrate recognition by serine proteases have focused on speci-ficities at the primary S1–Sn sites, but topological specificities (i.e. recogni-tion at distinct three-dimensional structural motifs) have not been established. This is the first report to identify the key amino acid residue conferring topological specificity.
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