Decoration of cyclodextrin on surface of porous nanosilica via Disulfide bond for the controlled drug release

The drug releasing behavior of the prepared DOX@PNS-SS-A/CD was also determined using dithiothretol (DTT) which was used to reduce –SS- in PNS-SS-A/CD. Additionally, MTT assay was performed to determine whether the PNS-SS-A/CD may reduce the toxicity to HeLa cells of DOX. The aim of this study is to create an efficiency redoxsensitive PNS for controlled drug delivery.