Drug delivery system

The nasal route for drug administration has the potential for local and systemic delivery of a wide variety of therapeutics. Nasal spray drug delivery has the potential to administer drugs to the bloodstream, avoiding the use of painful needles. While there is great potential, studies in the area are limited and somewhat conflicting. This study aimed to support the improvement of nasal drug delivery through experimental work on a model nasal cavity and through experimental characterisation of nasal spray behaviour. Four different brands of nasal spray were investigated.

91p runthenight04 02-02-2023 8 3   Download

The nasal route for drug administration has the potential for local and systemic delivery of a wide variety of therapeutics. Nasal spray drug delivery has the potential to administer drugs to the bloodstream, avoiding the use of painful needles. While there is great potential, studies in the area are limited and somewhat conflicting. The thesis "Experimental Studies in Aid of Improving Nasal Drug Delivery" aimed to support the improvement of nasal drug delivery through experimental work on a model nasal cavity and through experimental characterisation of nasal spray behaviour.

91p runordie3 06-07-2022 5 3   Download

Research purpose: Preparation and characterization of nanocarrier systems for drug delivery system based on the modification of dendrimer (PAMAM) with biocompatible surfaces such as PNIPAM and PAA to improve the capping cisplatin.

30p extraenglish 24-05-2021 19 4   Download

Research purpose: Preparation and characterization of nanocarrier systems for drug delivery system based on the modification of dendrimer (PAMAM) with biocompatible surfaces such as PNIPAM and PAA to improve the capping cisplatin.

30p capheviahe27 23-02-2021 16 4   Download

The study has indicated that MOFs has maintained extensive applications in Biological imaging and sensing, Drug delivery systems, Methane storage, Semiconductors, Bio-mimetic mineralization, Carbon capture, Desalination/ion separation, Water vapor capture and Ferroelectrics and Multiferroics.

20p tocectocec 25-05-2020 20 1   Download

A bio-nanocapsule (BNC), composed of the surface antigen (sAg) of the hepatitis B virus, is an efficient nanomachine with which to accomplish the liver-specific delivery of genes and drugs. Approximately 110 molecules of sAg are associated to form a BNC particle with an average diameter of 130 nm. TheLprotein is an sAg peptide composed mainly of preS and S regions. The preS region, with specific affinity for human hepatocytes, is localized in the N-terminus.

10p fptmusic 11-04-2013 37 2   Download

Polymeric micelle, the self-assembly of block copolymers with core-shell architecture, is a promising nanocarrier for drug and gene delivery. There are several relevant properties in polymeric micelle as nanocarrier systems, such as longevity in blood circula-tion, tissue-penetrating ability, spatial and temporal controlled drug release, and reduced inherent toxicity of cytotoxic reagents.

6p viettel02 22-02-2013 46 2   Download

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa hoc quốc tế đề tài : The application of carbon nanotubes in target drug delivery systems for cancer therapies

22p dauphong11 06-02-2012 74 8   Download

Ovarian cancer is the leading cause of death among women with gynecologic malignancies in the United States. Advanced ovarian cancers are difficult to cure with the current available chemotherapy, which has many associated systemic side effects. Doxorubicin is one such chemotherapeutic agent that can cause cardiotoxicity. Novel methods of delivering chemotherapy without significant side effects are therefore of critical need.

12p toshiba23 18-11-2011 54 4   Download

The treatment of AIDS remains a serious challenge owing to high genetic variation of Human Immunodeficiency Virus type 1 (HIV-1). The use of different antiretroviral drugs (ARV) is significantly limited by severe side-effects that further compromise the quality of life of the AIDS patient. In the present study, we have evaluated a liposome system for the delivery of nevirapine, a hydrophobic non-nucleoside reverse transcriptase inhibitor. Liposomes were prepared from egg phospholipids using thin film hydration.

9p toshiba23 18-11-2011 45 3   Download