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Báo cáo khoa học: The specific delivery of proteins to human liver cells by engineered bio-nanocapsules

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:10

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A bio-nanocapsule (BNC), composed of the surface antigen (sAg) of the hepatitis B virus, is an efficient nanomachine with which to accomplish the liver-specific delivery of genes and drugs. Approximately 110 molecules of sAg are associated to form a BNC particle with an average diameter of 130 nm. TheLprotein is an sAg peptide composed mainly of preS and S regions. The preS region, with specific affinity for human hepatocytes, is localized in the N-terminus.

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Nội dung Text: Báo cáo khoa học: The specific delivery of proteins to human liver cells by engineered bio-nanocapsules

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