Decreases in paraoxonase-1 activities promote a pro-inflammatory effect of lipids peroxidation products in non-smoking and smoking patients with acute pancreatitis

The study investigated the extent to which tobacco smoke exposure causes changes in lipids biochemistry through measurement blood concentrations of: paraoxonase-1 (PON-1) activities as lipid-bound enzyme into cell membrane, concentration of malonyldialdehyde (MDA), protein adducts of 4-hydroxynonenal (HNE-adducts), oxidized low density lipoproteins (oxLDL),...