Ebook Transgenic mouse - Methods and protocols (2/E): Part 1

Part 1 book "Transgenic mouse - Methods and protocols" includes content: Introduction - Strategies for developing genetically modified mice; genetic modification of the mouse - general technology – pronuclear and blastocyst injection; generation of chimeras by aggregation of embryonic stem cells with diploid or tetraploid mouse embryos; cryopreservation of mouse spermatozoa and in vitro fertilization; autopsy and histological analysis of the transgenic mouse; transgene design; inducible transgenic mouse models; lentiviral transgenesis; transgenesis in mouse embryonic stem cells.