Fabrication and structural characterization of self-crosslinking hydrogel based on Vietnamese sources of chitosan and alginate

Hydrogel materials have attracted extensive research over the last few decades, especially in tissue engineering, due its many comparable properties with native tissue. This study proposes a new approach to hydrogel fabrication that combines oxidized alginate (OA) into N,O-carboxymethyl chitosan (NOCC) and an oxidized hyaluronan-based hydrogel system employing low cost, domestically sourced chitosan and alginate.