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GPU accelerated sequence alignment with traceback for GATK HaplotypeCaller

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Pairwise sequence alignment is widely used in many biological tools and applications. Existing GPU accelerated implementations mainly focus on calculating optimal alignment score and omit identifying the optimal alignment itself. In GATK HaplotypeCaller (HC), the semi-global pairwise sequence alignment with traceback has so far been difficult to accelerate effectively on GPUs.

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Nội dung Text: GPU accelerated sequence alignment with traceback for GATK HaplotypeCaller

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