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Identification of recurrent focal copy number variations and their putative targeted driver genes in ovarian cancer

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Genomic regions with recurrent DNA copy number variations (CNVs) are generally believed to encode oncogenes and tumor suppressor genes (TSGs) that drive cancer growth. However, it remains a challenge to delineate the key cancer driver genes from the regions encoding a large number of genes.

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Nội dung Text: Identification of recurrent focal copy number variations and their putative targeted driver genes in ovarian cancer

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