Multivariate regression models based on UV full spectra for the simultaneous determination of tetracycline, penicillin G and cephalexin in different dosage forms

In this study, one analytical procedure was established for simultaneous determination based on UV-Vis spectrometry coupled with several multivariate linear regress solved by Python – an open language programme to quantify three antibiotics, including TET, PGP, and CEX, in laboratoryprepared synthetic and pharmaceutical mixtures. This study also provided a universally analytical procedure for determining the three antibiotics in their pharmaceutical forms without the need for optimization for each analyte.