Polymorphism of FCN2 gene and serum ficolin-2 levels in Dengue hemorrhagic fever patients

To evaluate the role of FCN2 polymorphism and ficolin-2 protein concentration in pathophysiological disorders in dengue fever; 278 patients with Dengue patients were collected in the 2017 outbreak at Military Hospital 103, diagnosed and grouped according to the “Guidelines for diagnosis and treatment for Dengue of Vietnam Ministry of Health” in 2011, the polymorphisms in the promoter region and exon 8 were determined by Sanger sequencing method. Serum ficolin-2 protein concentration was determined by ELISA method.