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Pre-operative denosumab is associated with higher risk of local recurrence in giant cell tumor of bone: A systematic review and meta-analysis
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In 2013, denosumab was introduced as peri-operative adjuvant treatment for giant cell tumor (GCT) of bone as it inhibits osteoclast activity. It is suggested that denosumab relives pain, facilitate curettage in lesions requiring resection initially.
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