Regulation of the tumour suppressor PDCD4 by miR-499 and miR-21 in oropharyngeal cancers

The rates of oropharyngeal cancers such as tonsil cancers are increasing. The tumour suppressor protein Programmed Cell Death Protein 4 (PDCD4) has been implicated in the development of various human cancers and small RNAs such as microRNAs (miRNAs) can regulate its expression.