Structural effects of sprifermin in knee osteoarthritis: A post-hoc analysis on cartilage and non-cartilaginous tissue alterations in a randomized controlled trial

A recent publication on efficacy of Sprifermin for knee osteoarthritis (OA) using quantitatively MRI-defined central medial tibio-femoral compartment cartilage thickness as the structural primary endpoint reported no statistically significant dose response.