Unique adaptations in neonatal hepatic transcriptome, nutrient signaling, and onecarbon metabolism in response to feeding ethyl cellulose rumen-protected methionine during late-gestation in Holstein cows

Methionine (Met) supply during late-pregnancy enhances fetal development in utero and leads to greater rates of growth during the neonatal period. Due to its central role in coordinating nutrient and one-carbon metabolism along with immune responses of the newborn, the liver could be a key target of the programming effects induced by dietary methyl donors such as Met.