Activity restrictions
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Ebook "Biotechnology and bioforensics: New trends" has come up with its horizons widened. It aims to bring out all the advancements and innovations in the field of Biology, not restricting itself only to DNA technologies. The chapters in the book have brought together interdisciplinary domains of Life Science to implement the developments in one discipline so as to foster the standards of the other.
90p tudohanhtau1006 29-03-2024 6 1 Download
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Notch3 restricts metastasis of breast cancers through regulation of the JAK/STAT5A signaling pathway
To explore the potential role of signal transducer and activator of transcription 5A (STAT5A) in the metastasis of breast cancer, and its mechanism of regulation underlying. Methods and results TCGA datasets were used to evaluate the expression of STAT5A in normal and different cancerous tissues through TIMER2.0, indicating that STAT5A level was decreased in breast cancer tissues compared with normal ones.
15p vileonardodavinci 23-12-2023 6 3 Download
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The paper employed Software for Market Analysis and Restrictions on Trade (SMART) to assess trade effects of EVFTA on the exportation of Vietnamese fishery products to the Netherlands once the agreement is fully activated for all types of marine food in 2027.
14p viindra 06-09-2023 12 6 Download
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Iron is a crucial element for bacterial survival and virulence. During Salmonella infection, the host utilizes a variety of mechanisms to starve the pathogen from iron. However, Salmonella activates distinctive defense mechanisms to acquire iron and survive in iron-restricted host environments.
14p vihagrid 30-01-2023 7 3 Download
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Chitosan is a polysaccharide with recognized antioxidant, antimicrobial and wound healing activities. However, this polymer is soluble only in dilute acidic solutions, which restricts much of its applications.
11p vihermione 06-01-2023 7 2 Download
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An important motivation for the use of nanomaterials and nanoarchitectures in cancer therapy emanates from the widespread emergence of drug resistance. Although doxorubicin (DOX) induces cell cycle arrest and DNA damage by suppressing topoisomerase activity, resistance to DOX has severely restricted its anti-cancer potential.
21p viginny 30-12-2022 7 2 Download
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Sensory processing is essential for the interaction with the environment and for adequate daily function. Sensory processing may deteriorate with aging and restrict daily activity performance. Aging may also affect Executive functions (EFs) which are critical for daily activity performance.
10p viisaacnewton 25-04-2022 17 4 Download
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Music-based interventions (MBI), using music as a therapeutic medium, has been utilized as a promising strategy for motor relearning and shaping. However, currently, MBI with active performance training is restricted to being extensively applied for patients with various levels of defects in fine motor skills and cognitive functions.
9p vinobelprisen 26-03-2022 19 3 Download
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Fear of falling (FoF) has far-reaching implications including activity restriction, functional decline and reduced quality of life. It is a common consequence of falls but may be present even in non-fallers. This study aimed to determine the factors associated with FoF in a segment of Singapore’s community-dwelling older adults.
10p vinobelprisen 26-03-2022 11 4 Download
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Lactic acid produced by tumors has been shown to overcome immune surveillance, by suppressing the activation and function of T cells in the tumor microenvironment. The strategies employed to impair tumor cell glycolysis could improve immunosurveillance and tumor growth regulation. Dichloroacetate (DCA) limits the tumorderived lactic acid by altering the cancer cell metabolism.
12p vielonmusk 21-01-2022 6 0 Download
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The clinical use of cisplatin, which is a first-line anticancer agent, is highly restricted due to its adverse effects on kidneys that lead to nephrotoxicity. Therefore, some potential reno-protective substances have been used in combination with cisplatin to cope with nephrotoxicity. Due to its high antitumor activity and oxygen-carrying capacity, we investigated the molecular effects of squalene against cisplatin-induced oxidative stress and kidney damage in mice. Single dose of cisplatin (7 mg/kg) was given to male Balb/c mice.
10p thiencuuchu 27-11-2021 15 1 Download
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Because breast cancer is complicated at the pathological, histological, clinical, and molecular levels, identification of new genetic targets against carcinogenic pathways is required to generate clinically relevant treatment options. Restriction of USP7 activity strongly enhanced apoptotic gene expression and reduced metastatic ability of breast cancer cell lines. This study describes one potential molecular target for the suppression of breast cancer proliferation and metastasis.
15p thiencuuchu 27-11-2021 6 1 Download
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Acoustic or hydrodynamic shearing, sonication and enzymatic digestion are used to fragment DNA. However, these methods have several disadvantages, such as DNA damage, difficulties in fragmentation control, irreproducibility and under-representation of some DNA segments. The DNA fragmentation tool would be a gentle enzymatic method, offering cleavage frequency high enough to eliminate DNA fragments distribution bias and allow for easy control of partial digests.
11p vibeauty 23-10-2021 9 1 Download
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The interferon-induced transmembrane (IFITM) protein family comprises a class of restriction factors widely characterised in humans for their potent antiviral activity. Their biological activity is well documented in several animal species, but their genetic variation and biological mechanism is less well understood, particularly in avian species.
14p visilicon2711 20-08-2021 14 1 Download
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Most animals restrict their activity to a specific part of the day, being diurnal, nocturnal or crepuscular. The genetic basis underlying diurnal preference is largely unknown. Under laboratory conditions, Drosophila melanogaster is crepuscular, showing a Bimodal activity profile.
11p vijeeni2711 30-06-2021 7 1 Download
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The goal of the Thesis: Investigate the current status of the trawl fishing, evaluate the invasive level of the trawlers to the fisheries resources and propose solutions to limit the fishing activities to protect the fisheries resources in the coastal areas of Van Don district, Quang Ninh province.
24p tunelove 11-06-2021 13 4 Download
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Glypican-1 is a heparan sulfate proteoglycan that is overexpressed in prostate cancer (PCa), and a variety of solid tumors. Importantly, expression is restricted in normal tissue, making it an ideal tumor targeting antigen.
13p vichaeng2711 29-04-2021 8 1 Download
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Low back pain (LBP) is a significant public health problem in Western industrialised countries and has been reported to affect up to 80% of adults at some stage in their lives. It is associated with high health care utilisation costs, disability, work loss and restriction of social activities.
8p viannito2711 20-04-2021 12 1 Download
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Falls, associated injuries and fear-of-falling are common in adults with RA. Fear-of-falling can be a major consequence of, and as debilitating as falling, resulting in a cycle of activity restriction, reduced quality of life, institutionalisation and potentially increase risk of falls.
11p vianttinic2711 20-04-2021 8 3 Download
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Arthroscopic glenohumeral debridement for symptom control has shown promising short term results in the young active population, when arthroplasty may not be a practical option due to the recommended activity restrictions, potential for complications and/or early wear, and a need for revision.
7p vianttinic2711 20-04-2021 12 2 Download