Adrenal steroid hormones

Obesity is associated with many chronic diseases including cortisol rhythm disorder and low testosterone. Furthermore, studies on obese children are quite limited and no concordance results have been obtained, especially for boys in puberty. Moreover, the sample sizes of previous studies were small, and were not representative.

8p virome2711 13-01-2020 10 0   Download

Dehydroepiandrosterone (DHEA), the most abundant sex steroid, is primarily secreted by the adrenal gland and a precursor hormone used by athletes for performance enhancement. Whole-body vibration (WBV) is a well-known light-resistance exercise by automatic adaptations to rapid and repeated oscillations from a vibrating platform, which is also a simple and convenient exercise for older adults.

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Objectives: To investigate whether the pituitary-adrenal axis may be altered under long-term inflammation of rheumatoid arthritis as well as the effect of steroid administration. Subjects and methods: Concentration of blood adrenocorticotropic hormone and cortisol were measured in 140 rheumatoid arthritis patients and 60 people used as control group.

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Although the role of arachidonic acid (AA) in the regulation of steroidogenesis is well documented, the mechanism for AArelease isnot clear.Therefore, theaimof this studywas to characterize the role of an acyl-CoA thioesterase (ARTISt) and an acyl-CoA synthetase as members of an alternative pathway in the regulation of the intracellular levels of AA in steroidogenesis. Purified recombinant ARTISt releases AA from arachidonoyl-CoA (AA-CoA) with a Kmof 2lM.

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Some adenomas produce too much adrenal steroid hormones. Sometimes the excess hormone can cause symptoms. Many of the hormone-related symptoms of adenomas are the same as those from adrenal carcinomas (cancers). These symptoms are discussed in the sections, “Can adrenal cancer be found early?” and “How is adrenal cancer diagnosed?” Adenomas are much more likely than carcinomas to produce high levels of aldosterone, which can cause high blood pressure. Treatment: Adenomas can be cured by removing the adrenal gland that contains the adenoma.

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Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Steroid hormone receptors ERα and PR characterised by immunohistochemistry in the mare adrenal gland...

9p coxanh_1 22-10-2011 60 3   Download

Corticoid là hormon vỏ thượng thận, xuất phát từ chữ adrenal cortex. Do trong công thức cấu tạo có nhân steroid nên còn được gọi là glucocorticoid (GC)( tên chung cho các hormon của vỏ thượng thận ). 2.1. Nguồn gốc : + Thiên nhiên : phân lập từ tuyến vỏ thượng thận các động vật lớn. + Tổng hợp hoặc bán tổng hợp : từ acid desoxycholic mật, từ thực vật ( từ sarmentogenin của cây Strophantus, từ botogemis của cây Dioscorea mexicana). Mọi GC đang dùng trong điều trị đều là dẫn xuất của cortisol. ...

25p thiuyen10 06-09-2011 714 62   Download

Cushing's Syndrome is a disease caused by an excess of cortisol production or by excessive use of cortisol or other similar steroid (glucocorticoid) hormones. Cortisol is a normal hormone produced in the outer portion, or cortex, of the adrenal glands, located above each kidney. The normal function of cortisol is to help the body respond to stress and change. It mobilizes nutrients, modifies the body's response to inflammation, stimulates the liver to raise the blood sugar, and it helps control the amount of water in the body.

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Hormonal Evaluation Androgens are secreted by the ovaries and adrenal glands in response to their respective tropic hormones, luteinizing hormone (LH) and adrenocorticotropic hormone (ACTH). The principal circulating steroids involved in the etiology of hirsutism are testosterone, androstenedione, and dehydroepiandrosterone (DHEA) and its sulfated form (DHEAS). The ovaries and adrenal glands normally contribute about equally to testosterone production.

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Adrenocortical steroids and their synthetic analogues Mechanisms of action Actions: mineralocorticoid, glucocorticoid Individual adrenal steroids Pharmacokinetics Dosage schedules Choice of adrenal steroid Adverse effects of systemic pharmacotherapy Adrenal steroids and pregnancy Precautions during chronic therapy: treatment of intercurrent illness Dosage and routes of administration Indications for use Uses: replacement therapy, pharmacotherapy Withdrawal of pharmacotherapy . Inhibition of synthesis of adrenal steroids. Competitive antagonism .

17p bigbaby87 03-09-2010 77 11   Download