Age-related diseases

The degradation of epigenetic control with age is associated with progressive diseases of ageing, including cancers, immunodeficiency and diabetes. Reduced caloric intake slows the effects of ageing and agerelated disease in vertebrates and invertebrates, a process potentially mediated by the impact of caloric restriction on epigenetic factors such as DNA methylation.

11p visilicon2711 20-08-2021 4 1   Download

Neurodegenerative disorders are common and devastating. Rationally, the most effective treatments will target pathogenetic mechanisms. While alternative approaches, based on alleviating the symptoms of patients with Alzheimer disease, Parkinson disease, Huntington disease, prion disorders or amyotrophic lateral sclerosis, can be expected to reduce suffering, studies of pathogenesis of these agerelated disorderswill be most important for enabling early diagnosis and the creation of preventative and curative treatments.

199p crius75 04-01-2013 43 2   Download