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Aldehyde dehydrogenase
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Ebook "Adult stem cells: Biology and methods of analysis" offers readers a historical perspective as well as unique insights into cutting-edge thoughts. The volume contextualizes the recent discovery of stem/progenitor cell populations resident in many adult tissues and organs. It confronts the complexities scientists face in trying to validate these cells, while it also describes and critically evaluates the methods currently used to assess stem cell self-renewal.
282p
tracanhphuonghoa1007
22-04-2024
5
2
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Ebook "Acetic acid bacteria: Fundamentals and food applications" written by leading international authorities in the field, covers all the basic and applied aspects of acetic acid bacteria. It describes the importance of acetic acid bacteria in food industry by giving information on the microbiological properties of fermented foods as well as production procedures. Special attention is given to vinegar and cocoa, which are the most familiar and extensively used industrial applications of acetic acid bacteria.
359p
lucchinguyen
28-12-2023
4
2
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Tumor resistance is a global challenge for tumor treatment. Cancer stem cells (CSCs) are the main population of tumor cells for drug resistance. We have reported that high aldehyde dehydrogenase (ALDH) activity represents a functional marker for cervical CSCs.
13p
vikolindagrabar
27-07-2022
4
1
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Tear film (TF) helps maintain and protect ocular function against damage to the ocular surface. Proteins are one of its main constituents, whose expression pattern can be used as a biomarker of ocular changes and systemic diseases.
16p
vidarwin
22-02-2022
15
1
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The aim of this study was to confirm the presence of BADH gene and control whether it plays an important role to protect white clover (Trifolium repens L.) against oxidative, salt, and drought stresses. Three genotypes possessing BADH and 1 genotype lacking BADH were selected, considering the expression levels of BADH in response to methyl viologen mediated oxidative stress. The genotypes possessing BADH displayed significantly less ion leakage under oxidative stress treatment, compared to that lacking BADH.
8p
tudichquannguyet
29-11-2021
9
1
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Alcohol consumption is a major risk factor for esophageal cancer; however, a high incidence of esophageal cancer is observed particularly among Eastern Asians, although they consume relatively less alcohol, presumably due to the high frequency of aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphisms.
6p
vianrose2711
27-04-2021
8
1
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Bài viết phân tích sự tăng sinh tế bào (MTT), chúng tôi đã chỉ ra rằng curcumin có khả năng ức chế rõ rệt sự tăng sinh của tế bào ung thư dạ dày MKN45. Các phân tích bằng Flow cytometry cho thấy rằng, curcumin đã làm tăng tỷ lệ % tế bào apoptosis từ 27% đến 56% ở các nồng độ từ 10µM - 20µM và làm xuất hiệu kiểu nhân điển hình của tế bào apoptosis. Xa hơn nữa, nghiên cứu này đã chỉ ra rằng, curcumin đã điều hòa giảm sự biểu hiện của protein aldehyde dehydrogenase trong tế bào ung thư dạ dày MKN45.
8p
nguathienthan9
08-12-2020
30
0
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Myxofibrosarcoma comprises a spectrum of malignant neoplasms withprominent myxoid stromata, cellular pleomorphism, and distinct curvilinear vascular patterns. These neoplasms mainly affect patients in the sixth to eighth decades of life and the overall 5-year survival rate is 60–70%.
11p
vijennie2711
29-09-2020
14
1
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Conventional chemotherapy in malignant pleural mesothelioma (MPM) has minimal impact on patient survival due to the supposed chemoresistance of cancer stem cells (CSCs). We sought to identify a sub-population of chemoresistant cells by using putative CSC markers, aldehyde dehydrogenase (ALDH) and CD44 in three MPM cell lines; H28, H2052 and Meso4.
13p
virose2711
24-09-2020
14
0
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Aldehyde dehydrogenase 1 family member A1 (ALDH1A1) has been identified as a putative cancer stem cell (CSC) marker in breast cancer. However, the clinicopathological and prognostic significance of this protein in breast cancer patients remains controversial.
11p
virose2711
22-09-2020
18
2
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Aldehyde dehydrogenase 1 family member A1 (ALDH1A1) is a cancer stem cell marker, and its expression correlates with prognosis in a number of malignancies. The aim of this study is to determine the relationship of ALDH1A1 expression with clinicopathological parameters and prognosis in gastric cancer.
8p
vilisa271
22-09-2020
14
1
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Aldehyde dehydrogenase 1 (ALDH1) is widely used as a specific cancer stem cell marker in a variety of cancers, and may become a promising target for cancer therapy. However, the role of its expression in tumor cells and the microenvironment in different cancers is still controversial.
10p
viamsterdam
18-09-2020
10
1
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The successful targeting of neuroblastoma (NB) by associating tumor-initiating cells (TICs) is a major challenge in the development of new therapeutic strategies. The subfamily of aldehyde dehydrogenases 1 (ALDH1) isoenzymes, which comprises ALDH1A1, ALDH1A2, and ALDH1A3, is involved in the synthesis of retinoic acid, and has been identified as functional stem cell markers in diverse cancers.
13p
vimale2711
25-08-2020
16
2
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Tumor recurrence and metastasis are the most common reason for treatment failure. Metastasis-associate in colon cancer-1 (MACC1) has been identified as a metastatic and prognostic biomarker for colorectal cancer and other solid tumors. Aldehyde dehydrogenase 1 (ALDH1), a marker of cancer stem cells, is also associated with metastasis and poor prognosis in many tumors.
8p
vimale2711
25-08-2020
10
2
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Osteosarcoma (OS) is the most common primary bone tumor, with a propensity to metastasize to the lungs. Five-year survival for metastatic OS is below 30%, and has not improved for several decades despite the introduction of multi-agent chemotherapy. Understanding OS cell migration to the lungs requires an evaluation of the lung microenvironment.
10p
vimale2711
21-08-2020
6
1
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It is not known whether stromal cells in benign breast tissue can mediate risk of breast cancer. We recently described aldehyde dehydrogenase 1 A1 (ALDH1) positive (+) cells in morphologically normal breast stroma of premenopausal women, and the data indicated that their distribution is associated with clinical risk factors for breast cancer.
13p
vibaku2711
22-07-2020
12
2
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Efficiency of colorectal carcinoma treatment by chemotherapy is diminished as the resistance develops over time in patients. The same holds true for 5-fluorouracil, the drug used in first line chemotherapy of colorectal carcinoma.
15p
vimanila2711
29-06-2020
26
0
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Changes in cellular metabolism are now recognized as potential drivers of cancer development, rather than as secondary consequences of disease. Here, we explore the mechanism by which metabolic changes dependent on aldehyde dehydrogenase impact cancer development.
15p
viputrajaya2711
22-06-2020
12
0
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Aldehyde dehydrogenase 1A3 (ALDH1A3) has been implicated in the survival and proliferation of prostate cancer cells.
8p
viorochimaru2711
30-05-2020
30
0
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Plant ALDH10 enzymes are aminoaldehyde dehydrogenases (AMADHs) that oxidize different ω-amino or trimethylammonium aldehydes, but only some of them have betaine aldehyde dehydrogenase (BADH) activity and produce the osmoprotectant glycine betaine (GB).
16p
viminato2711
22-05-2020
9
0
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