Anticarcinogenic agents

According to the results, CAPE decreased cell viability in the RKO cell line in a dose-dependent manner. Likewise, CAPE induced apoptotic cell death in approximately 40% of the RKO cells. Furthermore, CAPE treatment increased the Serine 15 (Ser15) and Serine 46 (Ser46) phosphorylation of p53, while decreased the survivin expression. The results suggested that CAPE induced apoptosis by regulating p53 phosphorylation, leading to inhibition of the survivin expression.

11p thiencuuchu 27-11-2021 3 1   Download

Resistance to therapeutic agents and the highly toxic side effects of synthetic drugs has spurred new research in the treatment of colon cancer, which has high morbidity and mortality ratios. This study aims to clarify the molecular mechanisms of the anticarcinogenic properties of methanol extract of Viburnum opulus L. (EVO)and its main active compound, trans-p-coumaric acid (p-CA), on human colon cancer cells (DLD-1, HT-29, SW-620, Caco-2) and healthy colon epithelial cells (CCD-18Co).

12p thiencuuchu 27-11-2021 4 0   Download

Turmeric is a spice that has been used extensively used in the different food sectors as a flavoring and coloring agent, in almost every cellular biological event, process includes in the gene expression, signaling and regulation.

6p cothumenhmong4 25-03-2020 14 1   Download

Numerous reports, including some from the National Research Council, have examined the relationship of diet to cancer. It is generally accepted that diet is a contributing factor to the onset or progression of some types of cancer and that a prudent selection of foods, including fruits and vegetables, and avoidance or decreased consumption of other foods might influence the risk to an individual of contracting cancer.

434p camchuong_1 11-12-2012 43 3   Download