Antimicrobial resistance

Kháng kháng sinh (Antimicrobial resistance - AMR) là nguyên nhân hàng đầu gây tử vong trên khắp thế giới. Nhằm tăng cường kiểm soát tỷ lệ nhiễm vi khuẩn đa kháng, nhiều giải pháp đã được áp dụng, trong đó có vai trò quan trọng của Dược về sử dụng kháng sinh hợp lý, Vi sinh về phát hiện sớm vi khuẩn mang gen đề kháng kháng sinh và Kiểm soát nhiễm khuẩn về thực hành cách ly phòng tránh lây nhiễm chéo. Bài viết trình bày đánh giá hiệu quả quy trình kiểm soát nhiễm vi khuẩn đa kháng có phối hợp giữa chương trình kiểm soát nhiễm khuẩn và quản lý sử dụng kháng sinh.

8p vibenya 23-10-2024 4 1   Download

This study contributes to the scientific data on binary combinations by investigating the synergistic antibacterial activity of the binary combination of MM or MQ EOs with thymol. This research is significant as it contributes to the global effort to combat antimicrobial resistance, providing a potential solution to this pressing public health challenge.

13p viling 11-10-2024 3 1   Download

This study aimed to determine subclinical mastitis (SCM) caused by bacterial species, using chromogenic culture media and to assess the antimicrobial resistance rate in the isolated bacteria. From March to December 2023, 143 milk samples were collected from 71 Holstein Friesian cows with SCM across seven dairy farms in Ho Chi Minh City and Binh Duong province.

13p vibecca 01-10-2024 2 2   Download

New antimicrobials are urgently needed to combat the threat of multidrug-resistant bacteria worldwide. Our study aimed to access the antimicrobial and cytotoxic profiles of endophytic actinomycetes associated with Cinnamomum cassia Presl taken from a mountainous region in the Northwest of Vietnam.

11p viling 27-09-2024 4 2   Download

In this study, we assessed the status of antibiotic resistance of H. pylori isolates to antimicrobial agents at Hospital of Hue University of Medicine and Pharmacy in Central Vietnam and identified the underlying molecular mechanisms related to tetracycline and amoxicillin resistance.

8p vifaye 20-09-2024 4 1   Download

Bài viết trình bày khảo sát định danh vi khuẩn phân lập dương tính theo mẫu bệnh phẩm và đáp ứng kháng sinh của vi khuẩn trong năm 2022 tại chổ, bệnh viện Đa khoa Tâm Trí Sài Gòn. Đề kháng kháng sinh (antimicrobial resistance-AMR) là sự thay đổi xảy ra theo thời gian của vi khuẩn, vi rút, nấm và ký sinh trùng làm cho các sinh vật này không còn đáp ứng với thuốc kháng sinh, dẫn đến điều trị nhiễm trùng trở nên khó khăn hơn và làm tăng nguy cơ lây lan bệnh, bệnh nặng nề hơn và tử vong.

7p viambani 18-06-2024 8 2   Download

The outcomes are to be compared with typical drugs given that compounds are examined against gram-positive and gram-negative strains of bacteria and fungus. Against bacterial strains, products with nitro, methyl, and bromo substituents in the p-position of the benzene ring, as well as products with the nitro group at the m-position, showed very excellent activities against bacterial strains, while compounds with chloro substituent at p-position and m-position demonstrated good activity against the fungal strains Aspergillus niger and Fusarium javanicum.

8p dianmotminh02 03-05-2024 7 2   Download

Cathelicidins include antimicrobial peptides (AMPs) and are involved in the innate immune defense against infections in mammals. Polymorphisms in the DNA sequence of cathelicidin genes could be relevant to inherited variations of host innate immunity, adaptation, and pathogen resistance. This study aims to investigate the sequence polymorphism of cathelicidin genes including CATHL2 and CATHL4 from local indigenous yellow cattle breeds of Vietnam.

11p dianmotminh02 03-05-2024 12 2   Download

The growth of waterborne pathogens and the discharge of partially treated or non-treated chemical waste has become a severe environmental and health risk. Conventional wastewater treatment methods have become less effective, and most current techniques require multiple stages for the disinfection of antimicrobial-resistant (AMR) pathogens and the combined removal of toxic, non-biodegradable, or emerging priority pollutants from wastewater.

273p runordie3 06-07-2022 16 2   Download

Higher resistance was observed in food samples than in clinical ones. Moreover, 13 and 3 multidrug resistant serotypes of Salmonella were identified for the first time in Lebanon in the food and clinical samples respectively, with three of them isolated from imported food samples.

5p mudbound 10-12-2021 9 1   Download

The purpose of the thesis research: Synthesis of new complexes of platinum and rare-earth elements containing quinoline's derivatives that are resistant to cancer cells, high antimicrobial activity or good fluorescence.

27p tunelove 10-06-2021 21 4   Download

The objectives of the thesis: Identify Salmonella isolated from pork, beef, and chicken meat at the retail markets in Hanoi. Determining antibiotic resistance characteristics of isolated Salmonella.

26p extraenglish 24-05-2021 31 3   Download

The objectives of the thesis: Identify Salmonella isolated from pork, beef, and chicken meat at the retail markets in Hanoi; determining antibiotic resistance characteristics of isolated Salmonella; analysis of related gene categories in multi-antibiotic resistant Salmonella.

26p larachdumlanat129 20-01-2021 17 5   Download

This study was conducted at Sasaki Animal Hospital in Ho Chi Minh City to manage this disease by the synthetic mesh implant. A 10-year castrated male Pomeranian (5.2 kg) was referred to clinical examination because of a 4-month complaint of the return of a mass at the perineal area.

9p larachdumlanat129 19-01-2021 12 2   Download

This study aimed to investigate the antimicrobial resistance of five major respiratory pathogens in pigs of Hubei province, China, from October to December, 2019. Antibiotic susceptibility testing for Streptococcus suis, Haemophilus parasuis, Pasteurella multocida, Bordetella bronchiseptica and Actinobacillus pleuropneumoniae was determined to representatives of relevant antibiotic classes.

6p larachdumlanat129 19-01-2021 10 1   Download

The objective was to assess the distribution of urinary tract bacterial pathogens and to determine the antibiotic susceptibility profile of the isolates in our setting. Single positive cultures with a colony count of >105 CFU on CLED medium were identified and their antibiotic sensitivity and resistance profile was depicted in the form of an antibiogram.

7p gaocaolon9 22-12-2020 19 3   Download

Among the other 12 inpatient MRSA isolates which had the pvl gene, nine were sensitive to most of the non- beta lactam antibiotics, whereas remaining three were resistant to most of the antibiotics except vancomycin and linezolid. The presence of pvl gene can no longer be used to discriminate between CA-MRSA and HA-MRSA.

5p kequaidan7 01-09-2020 13 2   Download

Antimicrobial resistance is an emerging challenge for health personnel and researchers. In such scenario, alternative strategies targeting novel ways to kill or inhibit growth of microbes are need of the hour. Antimicrobial peptide can be a promising candidate to deal with this crisis. Extracellular matrix protein vitronectin (Vn) is recently being established as a bactericidal agent against certain microbes. Caprine Vn has got few structural alterations as compare to human Vn.

7p nguaconbaynhay5 16-05-2020 16 2   Download

The decoy approach against nuclear factor kB (NF-kB) is a useful tool to alter NF-kB dependent gene expression using synthetic oligonucleotides (ODNs) carrying NF-kB specific cis-elements. Unfortunately, ODNs are not stable and need to be extensively modified to be used in vivo or ex vivo. We have previously evaluated the possible use of peptide nucleic acids (PNAs) as decoy molecules. The backbone of PNAs is composed of N-(2-aminoethyl)glycine units, rendering these molecules resistant to both nucleases and proteases.

10p system191 01-06-2013 42 4   Download

The Na + /H + exchanger is a ubiquitous membrane protein of bacteria, plants and mammals. The first isoform discov-ered (NHE1) is present on the mammalian plasma mem-brane and transports oneH + out of cells inexchange for one extracellular Na + . With solubilization in standard SDS/ PAGE buffer, this protein had a high tendency to aggregate when subjected to elevated temperature. The aggregates were stable and did not dissociate in high concentrations of SDSor 2-mercaptoethanol.

9p research12 29-04-2013 45 3   Download