Attenuated virus
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In this paper, we present the results of sequencing, analysis and comparison of changes in the genome betweenthe attenuated virus strain Hanvet1.vn and the original pathogenic strain 02HY in order to evaluate the genetic changes related to the virulence and immunogenicity of the vaccine.
8p vimulcahy 18-09-2023 5 3 Download
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Porcine reproductive and respiratory syndrome virus (PRRSV) is a serious viral disease of swine. At present, there are vaccines for the control of PRRSV infection, but the effect is not satisfactory. The recombination of attenuated vaccines causes significant difficulties with the prevention and control of PRRSV.
7p vigandhi 23-02-2022 14 1 Download
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: Porcine reproductive and respiratory syndrome virus (PRRSV) infection can cause severe reproductive failure in sows and respiratory distress in pigs of all ages, leading to major economic losses. To date, there are still no effective strategies to prevent and control PRRSV.
11p vidarwin 23-02-2022 11 1 Download
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Goose parvoviruses (GPVs) spread globally and cause a huge economic loss to the poultry industry. Although the attenuated GPV vaccines play a key role in preventing the disease caused by GPV, the molecular basis for the attenuation of GPV is barely known.
7p vidarwin 23-02-2022 9 1 Download
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Porcine epidemic diarrhea virus (PEDV), an intestinal coronavirus that causes acute diarrhea and high mortality in suckling piglets, can result in high economic losses in the swine industry. In recent years, despite the use of China’s current vaccine immunization strategy, multiple types of PEDV strains were still found in immunized swine herds.
10p vigandhi 23-02-2022 9 1 Download
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Infection with feline immunodeficiency virus (FIV) causes an immunosuppressive disease whose consequences are less severe if cats are co-infected with an attenuated FIV strain (PLV). We use virus diversity measurements, which reflect replication ability and the virus response to various conditions, to test whether diversity of virulent FIV in lymphoid tissues is altered in the presence of PLV.
14p vikentucky2711 24-11-2020 13 1 Download
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Phylogenetic relationship of the CSF cell culture vaccine virus has also been established with other known CSF reference vaccine viruses, lapinized as well as cell culture adapted strains.
9p caygaocaolon7 18-09-2020 11 0 Download
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The cytotoxicity and virus titration of chitosan nanoparticles encapsulated live PPR virus vaccine (PPRV-CS-NPs) was analyzed in this study. Live attenuated PPR virus vaccine (AR-87) was encapsulated in chitosan nanoparticles using ionic gelation technique. The PPRV-CS-NPs were tested for cytotoxicity study in Vero cells with different concentrations (1-40g).The cell viability was more than 80 per cent with all the concentration of the PPRV-CS-NPs tested. This indicates that the PPRV-CS-NPs are not toxic even in concentration higher than the required vaccine dose.
4p trinhthamhodang3 22-02-2020 10 1 Download
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Dengue virus belongs to the Flaviviridae family which also includes viruses such as the Zika, West Nile and yellow fever virus. Dengue virus generally causes mild disease, however, more severe forms of the dengue virus infection, dengue haemorrhagic fever (DHF) and dengue haemorrhagic fever with shock syndrome (DSS) can also occur, resulting in multiple organ failure and even death, especially in children.
11p vinasaki2711 12-11-2019 13 1 Download
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Preparation and characterisation of attenuated cold-adapted influenza A reassortants derived from the A/Leningrad/134/17/57 donor strain presents the assay was capable of detecting interference where the infectivity ratio for A/Len/17 and A/Beij/32 was 1:7. Progeny viruses were characterised genetically by amplification of defined regions within each of the six internal genes by PCR and identification of the products by restriction enzyme analysis.
9p thuyancn 01-06-2015 39 4 Download
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Mutant analysis by polymerase chain reaction and restriction enzyme cleavage (MAPREC) has been developed by Chumakov et al. for poliovirus to determine quantitatively the presence of genomic changes in particular nucleotide sequences that lead to virulence phenotypes of oral poliomyelitis vaccine (OPV or live attenuated vaccine) [1]. Afterwards, this RI (radioisotope) MAPREC was developed to non RI – MAPREC by Japan Poliomyelitis Research Institute in 1998 to compensate for some disadvantages of RI-MAPREC [2].
7p tuanloc_muido 11-12-2012 34 1 Download
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Wild type measles virus attenuation independent of type I IFN
12p dauphong7 13-01-2012 29 2 Download
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Tham khảo tài liệu 'báo cáo hóa học: " attenuation and efficacy of human parainfluenza virus type 1 (hpiv1) vaccine candidates containing stabilized mutations in the p/c and l genes"', luận văn - báo cáo phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả
13p dauphong7 13-01-2012 85 3 Download
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes
13p dauphong5 04-01-2012 67 4 Download
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Attenuation of vaccinia virus by the expression of human Flt3 ligand
15p dauphong3 26-12-2011 57 3 Download
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A highly attenuated recombinant human respiratory syncytial virus lacking the G protein induces long-lasting protection in cotton rats
10p dauphong3 26-12-2011 38 3 Download
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Improved hatchability and efficient protection after in ovo vaccination with live-attenuated H7N2 and H9N2 avian influenza viruses
10p dauphong1 21-12-2011 47 2 Download
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Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Respiratory syncytial virus infection in Fischer 344 rats is attenuated by short interfering RNA against the RSV-NS1 gene
0p toshiba20 12-11-2011 39 1 Download
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Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Attenuation of dengue virus infection by adeno-associated virus-mediated siRNA delivery
0p toshiba20 12-11-2011 55 3 Download
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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Reduced proviral loads during primo-infection of sheep by Bovine Leukemia virus attenuated mutants
13p toshiba16 27-10-2011 51 1 Download