Basic membrane protein A

Part 1 book "Biochemistry" includes content: Biochemistry - an evolving science, protein composition and structure, exploring proteins and proteomes, DNA, RNA and the flow of genetic information, exploring genes and genomes, exploring evolution and bioinformatics, hemoglobin - portrait of a protein in action, enzymes - basic concepts and kinetics, catalytic strategies, regulatory strategies, carbohydrates, lipids and cell membranes, membrane channels and pumps, signal transduction pathways.

455p oursky07 24-10-2023 10 4   Download

The thesis is structured as follows: In Chapter 1, the scientific literature is summarized within the scope of this study. Chapter 2 provides a comprehensive overview of the principles of the applied computational approaches in this study. Chapter 3 identifies the important residues of the LsIA/α7 nAChR complex that affect the interactions between the toxin and the membrane protein due to C-terminal carboxylation of LsIA. The effects of C-terminal modification of LsIA on interactions with α3β2 nAChR, involved in cardiovascular diseases, were also investigated in Chapter 4.

234p runthenight04 02-02-2023 6 2   Download

In this study, we investigated the mechanisms that lead to the production of proinflammatory mediators by the murine macrophage cell line, RAW264.7, when these cells are exposed in vitro to recombinant Borrelia burgdorferi basic membrane protein A (rBmpA).

7p vihasaki2711 12-11-2019 8 0   Download

A series of thylakoid membrane proteins, including PsbX, PsbY and PsbW, are synthesized with cleavable signal peptides yet inserted using none of the known Sec/SRP/Tat/ Oxa1-type insertion machineries. Here, we show that, although superficially similar to Sec-type signal peptides, these thylakoidal signal peptides contain very different determinants.

11p system191 01-06-2013 41 2   Download

UhpC is a membrane-bound sensor protein inEscherichia colirequired for recognizing external glucose-6-phosphate (Glc6P) and induction of the transport protein UhpT. Recently, it was shown that UhpC is also able to transport Glc6P.In this studywe investigatedwhether these transport and sensing activities are obligatorily coupled in UhpC.We expressed a His-UhpC protein in a UhpC-deficientE. coli strain and verified that this construct does not alter the basic biochemical properties of the Glc6Psensor system....

8p tumor12 20-04-2013 56 1   Download

Using solution NMR spectroscopy, three-dimensional structures have been obtained for an 18-residue synthetic polypeptide fragment of 18.5 kDa myelin basic protein (MBP, human residues Q81–T98) under three condi-tions emulating the protein’s natural environment in the myelin membrane to varying degrees: (a) an aqueous solution (100 mmKCl pH 6.5), (b) a mixture of trifluoroethanol (TFE-d2) and water (30 : 70% v⁄v), and (c) a dispersion of 100 mm dodecylphosphocholine (DPC-d38 , 1 : 100 pro-tein⁄lipid molar ratio) micelles....

14p dell39 27-03-2013 37 2   Download

Plastid envelope DNA-binding protein (PEND) is a DNA-binding protein with a chloroplast basic region-zipper domain at its N-terminus and a transmembrane domain at its C-terminus. The localization of PEND to the inner envelope membrane was demonstrated in a targeting experiment using isolated membranes and green fluorescent protein-tagged fusion pro-teins.

11p vinaphone15 27-02-2013 31 1   Download

Ever since their discovery adenoviruses have proven to be a tremendous asset to biologists. Through the study of the adenoviruses, we have learned not only about the virus structures, mechanisms of viral replication, but also about eukaryotic gene expression, alternative splicing, regulation of cell cycle progression, and apoptosis. In the last five years, there has been an explosion in the use of adenoviruses as vectors for gene transfer to a variety of mammalian cells.

334p thuytienvang_1 31-10-2012 39 3   Download

Although this book is far from being exhaustive, it conveys some of the novel ideas and directions in the membrane trafficking field through a combination of review, research, and technical articles. The book is organized in a series of chapters that will “transport” the reader from the endoplasmic reticulum, where proteins and lipids are synthesized, to the plasma membrane, where molecules are either delivered or internalized via endocytosis.

246p yeutinh98 22-09-2012 76 5   Download

Several new aspects have been highlighted: for example, a novel role for lipids as receptors which drive protein sorting, the diversity of the sorting events that occur at the level of the Golgi apparatus, and the cross talk between exocytosis and autophagy. Moreover, an interesting example of how the knowledge of these pathways is exploited to generate novel secretory routes to direct the synthesis of bio-molecules in “cell factories” is discussed.

268p yeutinh98 22-09-2012 66 16   Download

Hemolytic Anemias Due to Abnormalities of the MembraneCytoskeleton Complex The detailed architecture of the red cell membrane is complex, but its basic design is relatively simple (Fig. 101-2). The lipid bilayer, which incorporates phospholipids and cholesterol, is spanned by a number of proteins that have their hydrophobic transmembrane domains embedded in the membrane. Most of these proteins have hydrophilic domains extending toward both the outside and the inside of the cell.

6p thanhongan 07-12-2010 66 3   Download

Drugs li KT used in Hyperlipoproteinemias port vehicles in the aqueous media of lymph and blood. To this end, small amounts of lipid are coated with a layer of phospholipids, embedded in which are additional proteins—the apolipoproteins (A). According to the amount and the composition of stored lipids, as well as the type of apolipoprotein, one distinguishes 4 transport forms: Lipid-Lowering Agents Triglycerides and cholesterol are essential constituents of the organism.

12p bigbaby87 04-09-2010 126 10   Download