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Benzylamine derivatives
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Various thioxo-quinazolino[3,4-a]quinazolinones were prepared and evaluated for their cytotoxicity in MOLT-4 (lymphoblastic leukemia) and MCF-7 (breast adenocarcinoma) cell lines. Synthesis of the target compounds was started from isatoic anhydride. Successive reaction of isatoic anhydride with benzylamine and 2-nitrobenzaldehyde, reduction of the nitro group, and reaction with CS2 gave 12-benzyl-6-thioxo-6,7,11b,12-tetrahydro-13H-quinazolino[3,4-a]quinazolin13-one.
10p
langthannam
29-12-2021
9
0
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(bq) part 2 book “kucers’ the use of antibiotics” has contents: antifolate agents and other synthetic antibacterials, quinolones and fluoroquinolones, nitroimidazoles, anti-tuberculous drugs, polyenes, echinocandins, allylamines and benzylamine derivatives,… and other contents.
2979p
tieu_vu15
07-09-2018
24
1
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