Beta lactamase inhibitor combinations
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Antibiotic resistance has risen perilously in all parts of the world. The lack of appropriate therapeutics to encounter resistant pathogens has enhanced the urge for the development of either new antibiotics or different therapeutic combinations.
9p cothumenhmong3 22-02-2020 21 0 Download
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AmpC beta-lactamases hydrolyse penicillins, monobactams, cephalosporins and cephamycins. AmpC producers are resistant tobetalactam/betalactamase inhibitor combinations therapeutically. AmpC is generally underreported which leads to therapeutic failures and uncontrolled spread of these resistant strains. Hence, there is an increased need to detect AmpC routinely in the laboratory. To detect AmpC β-lactamase production among Enterobacteriaceae isolated from clinical samples and to compare different inducer substrate combinations for the detection of inducible Amp-C (iAmpC).
7p kethamoi2 15-12-2019 10 0 Download
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A retrospective examination was conducted to identify risk factors for in-hospital mortality of elderly patients (65 years or older) treated with the beta-lactam/beta-lactamase inhibitor combination antibiotic, ampicillin/sulbactam (ABPC/SBT).
5p viwashington2711 04-12-2019 12 2 Download