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Calcium antagonist

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  • Part 1 book "Cardiac drug therapy" includes content: Beta blockers: The cornerstone of cardiac drug therapy - beta blocker controversies, angiotensin converting enzyme inhibitors and angiotensin II receptor blockers, ACE inhibitor ARB controversies, calcium antagonists (calcium channel blockers). calcium antagonist controversies, diuretics, hypertension, hypertension controversies.

    pdf336p zizaybay1101 30-04-2024 5 2   Download

  • The nutrient uptake processes of K, Mg, and Ca are strongly antagonistic resulting in a deficiency of the depressed nutrient [14]. A deficiency of one element could imply a relative or absolute excess of the others resulting in an imbalance for the plants [3]. A sufficient Ca concentration in soil or nutrient solution is important; however, major cations frequently interfere with Ca uptake [1].

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  • Calcium channel blockers (CCBs) are widely used drugs that have a narrow therapeutic index. Even minor overdoses must be treated in-hospital due to the risk of severe hypotension and bradycardia.

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  • The octadecaneuropeptide (ODN; QATVGDVNTDRPG LLDLK) and its C-terminal octapeptide (OP; RPGLLDLK), which exert anxiogenic activity, have been previously shown to increase intracellular calcium concentration ([Ca21]i) in cultured rat astrocytes through activation of a metabotropic receptor positively coupled to phospholipase C. It has also been found that the [D -Leu5]OP analog possesses a weak antagonistic activity. The aim of the present study was to synthesize and characterize cyclic analogs of OP and [D -Leu5]OP.

    pdf13p system191 01-06-2013 30 3   Download

  • Post ischaemic cell calcium invasion has been described as one of the main causes of graft failure. Protective effects of calcium antagonists have been investigated but are not con-vincing and their mechanisms of action remain unclear. In this work we tested the protective effect of a new calcium inhibitor described to block a calcium current insensitive to all known calcium blockers. Specific mapacalcine receptors were first characterized on rat hepatocytesmembranes using the 125 I-labeledmapacalcine....

    pdf6p fptmusic 16-04-2013 32 1   Download

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