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Cancer syndrome
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In recent years, breast cancer (BC) incidence and mortality have been the highest in females. Menopause-like syndrome (MLS), arising from hypoestrogenism caused by endocrine therapy, signifcantly afects the quality of life for females. Traditional Chinese Medicine (TCM) has advantages in ameliorating MLS, but the efficacy of TCM in patients with BC has not been systematically evaluated.
19p
vishanshan
27-06-2024
1
1
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For chronic pain after thoracic surgery, optimal timing of its diagnosis and effective treatment remains unresolved, although several treatment options are currently available. We examined the efficacy and safety of mirogabalin, in combination with conventional pain therapy (nonsteroidal anti-infammatory drugs and/or acetaminophen), for treating peripheral neuropathic pain (NeP) after thoracic surgery.
15p
vishanshan
27-06-2024
1
1
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Myelodysplastic syndrome (MDS) is known to arise through the pathogenic bone marrow mesenchymal stem cells (MSC) by interacting with hematopoietic stem cells (HSC). However, due to the strong heterogeneity of MDS patients, it is difficult to find common targets in studies with limited sample sizes. This study aimed to describe sequential molecular changes and identify biomarkers in MSC of MDS transformation.
14p
vikoch
27-06-2024
1
1
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Part 2 book "Paediatric and adolescent gynaecology - A multidisciplinary approach" includes content: Disorders of growth and puberty, turner’s syndrome, androgen insensitivity syndromes, the XY female, the gynaecology of the major genitourinary anomalies, congenital adrenal hyperplasi, gynaecological cancers in childhood, late reproductive sequelae of treatment for childhood cancer.
377p
zizaybay1101
30-04-2024
4
2
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Part 2 book "Plastic surgery - Clinical problem solving" includes content: Hemangioma, congenital chest deformity, sternal wound infection, juvenile virginal hypertrophy of the breast (gigantomastia), gynecomastia, poland syndrome , tuberous breast deformity, subjective hypomastia, breast cancer, abdominal wall defect, postbariatric reconstruction, congenital melanocytic nevi, ischial pressure ulcer, sacral pressure ulcer, trochanteric pressure sore,... and other contents.
177p
muasambanhan10
03-04-2024
4
2
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Pathogenic variants in BRCA1 and BRCA2 (BRCA1/2) lead to increased risk of breast, ovarian, and other cancers, but most variant-positive individuals in the general population are unaware of their risk, and little is known about prevalence in non-European populations. We investigated BRCA1/2 prevalence and impact in the electronic health record (EHR)-linked BioMe Biobank in New York City.
12p
vibransone
28-03-2024
7
2
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Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures. Intriguingly, rapidly emerging data indicate that altered genes representing oncogenic drivers can also be found in sporadic non-malignant conditions, some of which have negligible and/or low potential for transformation to cancer.
19p
vibransone
28-03-2024
1
1
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Hutchinson-Gilford progeria syndrome (HGPS) is a progeroid disease characterized by the early onset of age-related phenotypes including arthritis, loss of body fat and hair, and atherosclerosis. Cells from affected individuals express a mutant version of the nuclear envelope protein lamin A (termed progerin) and have previously been shown to exhibit prominent histone modification changes.
16p
vibransone
28-03-2024
3
2
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Fecal microbiota transplantation (FMT) has demonstrated efficacy in treating inflammatory bowel diseases and irritable bowel syndrome in an increasing number of randomized controlled trials. Recently published data gives striking insights into the factors associated with FMT success paving the road for the use of precision medicine in gastrointestinal disorders.
4p
vibransone
28-03-2024
9
2
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DNA sequencing is increasingly incorporated into the routine care of cancer patients, many of whom also carry inherited, moderate/high-penetrance variants associated with other diseases. Yet, the prevalence and consequence of such variants remain unclear.
13p
vibransone
28-03-2024
4
2
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Germline variants affecting the proof reading activity of polymerases epsilon and delta cause a hereditary cancer and adenomatous polyposis syndrome characterized by tumors with a high mutational burden and a spe‑ cifc mutational spectrum.
18p
vicwell
29-02-2024
5
2
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Many families and individuals do not meet criteria for a known hereditary cancer syndrome but display unusual clusters of cancers. These families may carry pathogenic variants in cancer predisposition genes and be at higher risk for developing cancer.
16p
vicwell
29-02-2024
4
1
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Ebook Concise oral medicine: Part 2 includes content: Temporomandibular joint disorders, temporomandibular joint disorders, oral cancer and precancerous lesions, immunological diseases, forensic odontology, orofacial syndromes, differential diagnosis of miscellaneous diseases,… and other contents.
126p
longtimenosee03
01-02-2024
5
0
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Tumor lysis syndrome is an oncologic emergency that classically occurs following cancer therapy, although spontaneous tumor lysis syndrome can also occur in malignancies, albeit rarely. Spontaneous tumor lysis syndrome has previously been reported in some hematologic malignancies, but it rarely happens in solid tumors and seems to be associated with a higher mortality rate.
5p
vigojek
02-02-2024
3
1
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Oxaliplatin-based chemotherapy represents a standard of care in the treatment of metastatic colorectal cancer. We report a rare case of fulminant oxaliplatin-induced thrombotic microangiopathy, clinically suggestive of hemolytic–uremic syndrome, occurring in a female patient with a prolonged history of exposure to oxaliplatin for the treatment of metastatic colon cancer.
6p
vitiki
30-01-2024
6
2
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During the severe acute respiratory syndrome coronavirus 2 pandemic, several patient groups are at particular risk. Mortality is higher among cancer patients and may be increased further by thromboembolic events, which are more common in coronavirus 2019 patients according to recent publications.
7p
vitiki
30-01-2024
9
2
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At the time of benign gynecological surgery, a prophylactic salpingo-oophorectomy or salpingectomy is increasingly being performed concurrently to reduce the risk of future ovarian and fallopian tube cancer. We herein describe a case of hereditary breast and ovarian cancer syndrome in which a hysterectomy and bilateral adnexectomy were performed with a preoperative diagnosis of benign tumor.
6p
vitiki
30-01-2024
2
2
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Part 1 book "Withrow and MacEwen's small animal clinical oncology" includes content: The etiology of cancer; tumor biology and metastasis; the pathology of neoplasia; epidemiology and the evidence based medicine approach; paraneoplastic syndromes; diagnostic imaging in oncology; diagnostic cytopathology in clinical oncology; molecular diagnostics; biopsy and sentinel lymph node mapping principles;... and other contents.
387p
muasambanhan05
22-01-2024
4
2
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High-sensitivity C-reactive protein (hs-CRP) levels and metabolic syndrome (MetS) are known to be associated with an increased incidence of different cancers. We aimed to evaluate the effect of MetS combined with high hs-CRP levels on the risk of primary liver cancer (PLC).
12p
vimichaelfaraday
28-12-2023
6
3
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Part 2 book "Swine in the laboratory surgery, anesthesia, imaging, and experimental techniques" includes content: Toxicology, radiobiology, swine in cancer research, necropsy on research swine, use of swine in biomedical research, ossabaw island miniature swine - metabolic syndrome and cardiovascular assessment,... and other contents.
312p
muasambanhan03
25-12-2023
2
1
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