Cancer therapy

Prostate cancer (PC) with bone metastasis has many clinical symptoms that very much affected to the patient’s quality of life (QoL). Improving cancer patient’s QoL is a mission for the health care professional workers. The study using questionaires SF-36 and UCLA-PCI-SF- a simple and common methods to evaluate the progress of orchiectomy treatment for bone metastases PC to assess the QoL and prostate-specific functions before and after orchiectomy.

7p viyamanaka 06-02-2025 1 1   Download

There is limited data about the clinic-pathological features and the predictors of survival in gastric cancer patients who received adjuvant SOX post-operation in Vietnam. This study aimed to identify the correlation between clinic-pathological features and clinical outcomes for this population.

10p viyamanaka 06-02-2025 2 2   Download

Thyroid carcinomas are the most common endocrine malignancies. The cervical lymph node metastasis rate in patients with PTC ranges from 30-80% and there is a significant difference in survival at 14 years for those with and without lymph node metastases. Therefore, the early detection of metastatic cervical lymph nodes plays an essential role in deciding upon the optimal surgical treatment plan for the majority of patients, which will allow careful postoperative screening, adjuvant therapies, and minimizes the chance of disease recurrence, so we conducted this study.

6p vinara 11-01-2025 1 1   Download

Ostomy has become a common therapy for treating gastrointestinal diseases such as colorectal cancer. Patients with ostomy experience many problems including appearance change, uncontrolled discharge and odour, sexual dysfunction, decreased social functioning, and difficulties taking care of themselves. Because of these problems, many patients with ostomies feel anxious, unconfident and afraid to participate in social activities.

8p vinara 11-01-2025 1 1   Download

Helicobacter pylori (H.pylori) associated chronic gastritis is a risk factor of gastric cancer. This study aims to confirm effect of H.pylori eradication of sequential therapy (RA-RCT) and compare with the standard triple-drug therapy (RCT), addition to evaluating the improvement about histology of chronic gastritis after treatment.

7p viuchiha 06-01-2025 2 1   Download

Leukemia is the most common childhood cancer in both Vietnam and another country around the world. Although the rate of successful treatment has increased due to the improvements of therapy and supportive care, the rate of relapse is still high.

5p viuchiha 06-01-2025 3 1   Download

Colorectal cancer (CRC) is one of the most common malignant cancers of the colon worldwide. Several novel approaches to cancer treatment have emerged, including gene therapy, targeted therapy, and adjuvant therapies.

7p viharuno 03-01-2025 2 2   Download

To investigate clinical, paraclinical and 18F-FDGPET/CTimaging characteristics of postsurgical differentiated thyroid cancerpatients post RAI therapy with high serum thyroglobulin and negative 131I whole body scan. To determine the diagnostic values of 18 F-FDG-PET/CT in postsurgical differentiated thyroid cancer patients post RAI therapy with high serum thyroglobulin and negative 131 I whole body scan.

27p kequaidan12 03-06-2021 37 4   Download

To investigate clinical, paraclinical and 18F-FDGPET/CTimaging characteristics of postsurgical differentiated thyroid cancerpatients post RAI therapy with high serum thyroglobulin and negative 131I whole body scan. To determine the diagnostic values of 18 F-FDG-PET/CT in postsurgical differentiated thyroid cancer patients post RAI therapy with high serum thyroglobulin and negative 131 I whole body scan.

27p kequaidan7 01-09-2020 39 3   Download

To describe the clinical and subclinical features of lung cancer patients with EGFR mutations before TKIs therapy and in the relapsed period. To identify the T790M mutation and MET amplification in patients with lung cancer and EGFR-TKIs resistance and the relationship with clinical and subclinical features.

29p cothumenhmong6 17-07-2020 14 2   Download

Mời các bạn tham khảo bài thuyết trình Ứng dụng của laser trong Y học sau đây để nắm bắt được những nội dung về các đo bộ tạo phách của màng nhĩ (Heterodyne Measurements of Ear Drums), chuẩn đoán và chữa trị bệnh ung thư bằng liệu pháp HPD (Cancer Diagnostics and Therapy with the HPD Technique).

15p maiyeumaiyeu09 16-09-2016 279 46   Download

Numerous adhesion molecules have been described, and the molecular mechanisms of lymphocyte trafficking across the endothelium is starting to be elucidated. Identification of the molecules involved in the organoselec-tivity of this process would help in the targeting of drug therapy to specific tissues. Adhesion-regulating molecule-1 (ARM-1) is an adhesion-regulating molecule previously identified on T cells. It does not belong to any known families of adhesion molecules.

12p awards 06-04-2013 35 4   Download

Histone deacetylases are major regulators of eukaryotic gene expression. Not unexpectedly, histone deacetylases are among the most promising tar-gets in cancer therapy. However, despite huge efforts in histone deacetylase inhibitor design, very little is known about the impact of histone deacety-lase inhibitors on enzyme stability.

11p galaxyss3 19-03-2013 52 4   Download

The capsid protein of HIV-1 (p24) (CA) forms the mature capsid of the human immunodeficiency virus. Capsid assembly involves hexamerization of the N-terminal domain and dimerization of the C-terminal domain of CA (CAC), and both domains constitute potential targets for anti-HIV therapy.

13p galaxyss3 07-03-2013 47 4   Download

Solid tumours are complex structures in which the interdependent relation-ship between tumour and endothelial cells modulates tumour development and metastasis dissemination. The tumour microenvironment plays an important role in this cell interplay, and changes in its features have a major impact on tumour growth as well as on anticancer therapy respon-siveness.

12p galaxyss3 07-03-2013 48 3   Download

Epidermal growth factor receptor (EGFR)-mediated signal transduction is often hyperactivated in tumour cells and therefore considered a promising target for cancer therapy. A number of computational models have been developed which describe the pathway in great detail.

13p media19 04-03-2013 40 3   Download

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in a variety of tumour cells, but not in most normal cells, and has attracted considerable attention for its potential use in cancer therapy. Recently, increasing evidence has shown that TRAIL is involved in inflam-mation, although much of this evidence is controversial.

13p vinaphone15 27-02-2013 37 2   Download

d-Amino acid oxidase (DAAO) has recently become of interest as a biocat-alyst for industrial applications and for therapeutic treatments. It has been used in gene-directed enzyme prodrug therapies, in which its production of H2O2 in tumor cells can be regulated by administration of substrate. This approach is limited by the locally low O2 concentration and the high Km for this substrate.

12p vinaphone15 25-02-2013 30 2   Download

Pyrimidine biosynthesis enzymes function in many cellular processes and are closely associated with pyrimidine antagonists used in cancer chemo-therapy. These enzymes are well characterized from bacteria to mammals, but not in a simple metazoan. To study the pyrimidine biosynthesis path-way inCaenorhabditis elegans, we screened for mutants exhibiting resis-tance to the anticancer drug 5-fluorouracil (5-FU).

12p vinaphone15 25-02-2013 53 3   Download

The increasing number of chromosomal rearrangements involving the humanMLLgene, in combination with differences in clinical behavior and outcome for MLL-rearranged leukemia patients, makes it necessary to reflect on the cancer mechanism and to discuss potential therapeutic strate-gies. To date, 64 different translocations have been identified at the molecular level.

10p mobifone23 21-01-2013 57 4   Download