Cancer therapy

Colorectal cancer (CRC) is one of the most common malignant cancers of the colon worldwide. Several novel approaches to cancer treatment have emerged, including gene therapy, targeted therapy, and adjuvant therapies.

7p viharuno 03-01-2025 1 1   Download

To investigate clinical, paraclinical and 18F-FDGPET/CTimaging characteristics of postsurgical differentiated thyroid cancerpatients post RAI therapy with high serum thyroglobulin and negative 131I whole body scan. To determine the diagnostic values of 18 F-FDG-PET/CT in postsurgical differentiated thyroid cancer patients post RAI therapy with high serum thyroglobulin and negative 131 I whole body scan.

27p kequaidan12 03-06-2021 37 4   Download

To investigate clinical, paraclinical and 18F-FDGPET/CTimaging characteristics of postsurgical differentiated thyroid cancerpatients post RAI therapy with high serum thyroglobulin and negative 131I whole body scan. To determine the diagnostic values of 18 F-FDG-PET/CT in postsurgical differentiated thyroid cancer patients post RAI therapy with high serum thyroglobulin and negative 131 I whole body scan.

27p kequaidan7 01-09-2020 36 3   Download

To describe the clinical and subclinical features of lung cancer patients with EGFR mutations before TKIs therapy and in the relapsed period. To identify the T790M mutation and MET amplification in patients with lung cancer and EGFR-TKIs resistance and the relationship with clinical and subclinical features.

29p cothumenhmong6 17-07-2020 14 2   Download

Mời các bạn tham khảo bài thuyết trình Ứng dụng của laser trong Y học sau đây để nắm bắt được những nội dung về các đo bộ tạo phách của màng nhĩ (Heterodyne Measurements of Ear Drums), chuẩn đoán và chữa trị bệnh ung thư bằng liệu pháp HPD (Cancer Diagnostics and Therapy with the HPD Technique).

15p maiyeumaiyeu09 16-09-2016 279 46   Download

Numerous adhesion molecules have been described, and the molecular mechanisms of lymphocyte trafficking across the endothelium is starting to be elucidated. Identification of the molecules involved in the organoselec-tivity of this process would help in the targeting of drug therapy to specific tissues. Adhesion-regulating molecule-1 (ARM-1) is an adhesion-regulating molecule previously identified on T cells. It does not belong to any known families of adhesion molecules.

12p awards 06-04-2013 35 4   Download

Histone deacetylases are major regulators of eukaryotic gene expression. Not unexpectedly, histone deacetylases are among the most promising tar-gets in cancer therapy. However, despite huge efforts in histone deacetylase inhibitor design, very little is known about the impact of histone deacety-lase inhibitors on enzyme stability.

11p galaxyss3 19-03-2013 52 4   Download

The capsid protein of HIV-1 (p24) (CA) forms the mature capsid of the human immunodeficiency virus. Capsid assembly involves hexamerization of the N-terminal domain and dimerization of the C-terminal domain of CA (CAC), and both domains constitute potential targets for anti-HIV therapy.

13p galaxyss3 07-03-2013 46 4   Download

Solid tumours are complex structures in which the interdependent relation-ship between tumour and endothelial cells modulates tumour development and metastasis dissemination. The tumour microenvironment plays an important role in this cell interplay, and changes in its features have a major impact on tumour growth as well as on anticancer therapy respon-siveness.

12p galaxyss3 07-03-2013 46 2   Download

Epidermal growth factor receptor (EGFR)-mediated signal transduction is often hyperactivated in tumour cells and therefore considered a promising target for cancer therapy. A number of computational models have been developed which describe the pathway in great detail.

13p media19 04-03-2013 40 3   Download

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in a variety of tumour cells, but not in most normal cells, and has attracted considerable attention for its potential use in cancer therapy. Recently, increasing evidence has shown that TRAIL is involved in inflam-mation, although much of this evidence is controversial.

13p vinaphone15 27-02-2013 33 2   Download

d-Amino acid oxidase (DAAO) has recently become of interest as a biocat-alyst for industrial applications and for therapeutic treatments. It has been used in gene-directed enzyme prodrug therapies, in which its production of H2O2 in tumor cells can be regulated by administration of substrate. This approach is limited by the locally low O2 concentration and the high Km for this substrate.

12p vinaphone15 25-02-2013 30 2   Download

Pyrimidine biosynthesis enzymes function in many cellular processes and are closely associated with pyrimidine antagonists used in cancer chemo-therapy. These enzymes are well characterized from bacteria to mammals, but not in a simple metazoan. To study the pyrimidine biosynthesis path-way inCaenorhabditis elegans, we screened for mutants exhibiting resis-tance to the anticancer drug 5-fluorouracil (5-FU).

12p vinaphone15 25-02-2013 52 2   Download

The increasing number of chromosomal rearrangements involving the humanMLLgene, in combination with differences in clinical behavior and outcome for MLL-rearranged leukemia patients, makes it necessary to reflect on the cancer mechanism and to discuss potential therapeutic strate-gies. To date, 64 different translocations have been identified at the molecular level.

10p mobifone23 21-01-2013 54 4   Download

Multidrug resistance is a major challenge in the therapy of cancer and pathogenic fungal infections. More than three decades ago, P-glycoprotein was the first identified multidrug transporter. It has been studied exten-sively at the genetic and biochemical levels ever since. Pdr5, the most abun-dant ATP-binding cassette transporter in Saccharomyces cerevisiae,is highly homologous to azole-resistance-mediating multidrug transporters in fungal pathogens, and a focus of clinical drug resistance research. ...

10p mobifone23 18-01-2013 38 4   Download

It is becoming increasingly clear that signals generated in tumor microenvi-ronments are crucial to tumor cell behavior, such as survival, progression and metastasis. The establishment of these malignant behaviors requires that tumor cells acquire novel adhesion and migration properties to detach from their original sites and to localize to distant organs.

15p cosis54 05-01-2013 35 5   Download

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa hoc quốc tế đề tài : Encapsulation of docetaxel in oily core polyester nanocapsule intended for breast cancer therapy

24p sting03 06-02-2012 47 4   Download

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa hoc quốc tế đề tài : The application of carbon nanotubes in target drug delivery systems for cancer therapies

22p dauphong11 06-02-2012 75 8   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Encapsulation of docetaxel in oily core polyester nanocapsule intended for breast cancer therapy

24p dauphong6 05-01-2012 46 5   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences

18p dauphong4 03-01-2012 68 6   Download