Cancer type

Identify the mean SULmax level of the tumor in cervical cancer and compare the SULmax level between different histological types. Identify the mean size and mean SULmax level of metastatic lymph nodes in cervical cancer. Determine the percentage of cervical cancer patients with stage change after PET/CT. Determine the rate of accidental distant metastases detected by PET/CT.

8p viling 11-10-2024 2 1   Download

Gastric cancer (GC) is one of the common types of cancer in Vietnam. Over 50% of GCs are diagnosed at an unresectable stage. Deficiency in mismatch repair proteins (MMR) leading to microsatellite instability (MSI-H) is a crucial prognostic factor currently under investigation in these patients. This study aimed to determine the rate of MMR protein expression and its correlation with clinical characteristics, histopathological features, and overall survival in unresectable GC patients.

6p viengfa 29-09-2024 8 2   Download

Gastrointestinal cancers, including liver cancer, colorectal cancer, and stomach cancer, are the most common cancers in the world as well as in Vietnam, posing a leading threat to human health. The cost of treating these cancers is a major problem that burdens not only patients but also healthcare systems. The study aims to analyze treatment costs for the four most common types of gastrointestinal cancer nowadays.

9p vifaye 20-09-2024 3 1   Download

Leukemia is one of the most common types of cancer among children around the world. Acute lymphoblastic leukemia (ALL) accounts for approximately 75% of all cases of childhood leukemia. Acute lymphoblastic leukemia (ALL) remains the most common malignancy in children.

5p vinatisu 29-08-2024 2 1   Download

Pembolizumabis an immune check-point inhibitor to be targeted for Programmed cell death 1 (PD-1). It has been shown promising efficacy to various types of cancer. In Vietnam, pembrolizumab has been available since early of 2018. We has performed to treat certain types of cancer with pembrolizumabby now, herein we report the early experience with pembrolizumabin single institute in Vietnam.

4p vinatisu 29-08-2024 5 1   Download

Worldwide, childhood cancer is rare. In addition, a distinct variation in incidence, type distribution and the demographics. We conducted a study on the epidemiology of childhood cancer at Central Zone of Vietnam, in two hospitals: Hue Central Hospital and Danang Hospital of Women and Children, during the period of April 2014 - July 2019.

4p vinatisu 29-08-2024 1 1   Download

The research project deals with two different types of data for two separate analysis. The first analysis deals with normalised RNA-seq breast cancer data where machine learning techniques are used to classify and identify the biomarker of cancer. Second analysis deals with raw DNA methylated leukemia samples to determine the mutations.

102p runthenight04 02-02-2023 7 4   Download

Glioma is the most common primary intracranial tumour and has a very poor prognosis. Pyroptosis, also known as inflammatory necrosis, is a type of programmed cell death that was discovered in recent years. The expression and role of pyroptosis-related genes in gliomas are still unclear.

17p vielonmusk 21-01-2022 7 1   Download

Stomach adenocarcinoma (STAD), which accounts for approximately 95% of gastric cancer types, is a malignancy cancer with high morbidity and mortality. Tumor angiogenesis plays important roles in the progression and pathogenesis of STAD, in which long noncoding RNAs (lncRNAs) have been verified to be crucial for angiogenesis.

14p vielonmusk 21-01-2022 10 0   Download

It is a basic task in high-throughput gene expression profiling studies to identify differentially expressed genes (DEGs) between two phenotypes. RankComp, an algorithm, could analyze the highly stable withinsample relative expression orderings (REOs) of gene pairs in a particular type of human normal tissue that are widely reversed in the cancer condition, thereby detecting DEGs for individual disease samples measured by a particular platform.

11p vielonmusk 21-01-2022 14 1   Download

Colorectal cancer (CRC) is still one of the most common types of cancer in the world, and the gut microbiome plays an important role in its development. The microbiome is involved in the carcinogenesis, formation and progression of CRC as well as its response to different systemic therapies.

13p vielonmusk 21-01-2022 11 0   Download

Intrahepatic cholangiocarcinoma (ICC) is a type of malignant tumor ranking the second in the incidence of primary liver cancer following hepatocellular carcinoma. Both the morbidity and mortality have been increasing in recent years. Small duct type of ICC has potential therapeutic targets. But overall, the prognosis of patients with ICC is usually very poor.

12p vielonmusk 21-01-2022 17 1   Download

DNA repair deficiencies are characteristic of cancer and homologous recombination deficiency (HRD) is the most common. HRD sensitizes tumour cells to PARP inhibitors so it is important to understand the landscape of HRD across diferent solid tumour types. Methods: Germline and somatic BRCA mu

13p vielonmusk 21-01-2022 17 2   Download

BRCA gene mutations (BRCAm) have an impact on patients’ characteristics and clinical outcomes of ovarian cancer (OC). The frequency and patterns of BRCAm vary among countries and ethnicities. There are limited data from Saudi Arabia (SA); thus, this study aims to determine the frequency, pattern, and impact on patient characteristics and outcomes of BRCAm OC compared to wild-type BRCA (BRCAw) in Saudi women.

9p vielonmusk 21-01-2022 13 1   Download

Adult sporadic Burkitt lymphoma (BL) is a rare but highly aggressive subtype of lymphoma which lacks its own unique prognostic model. Systemic inflammatory biomarkers have been confirmed as prognostic markers in several types of malignancy. Our objective was to explore the predictive value of pretreatment inflammatory biomarkers and establish a novel, clinically applicable prognostic index for adult patients with sporadic BL.

11p vielonmusk 21-01-2022 16 1   Download

There is increasing evidence that combination therapy with nanoparticle albumin-bound paclitaxel (nab-paclitaxel) and programmed cell death protein 1 (PD-1) inhibitor is safe and efficacious in treating many types of malignant tumors. However, clinical data demonstrating the effect of this treatment combination for patients with metastatic soft tissue sarcoma (STS) are currently limited.

9p vielonmusk 21-01-2022 7 1   Download

To observe the clinicopathological and prognostic value of long non-coding RNA five prime to X inactive specific transcript (lncFTX) in multiple tumors. Methods: Eligible studies for lncFTX were identified by searching PubMed, Embase, Web of Science and Cochrane Library databases from inception to December 01, 2020. Stata 12.0 software was used to calculate the odds ratio (OR)/ hazard ratio (HR) and 95% confidence interval (95% CI).

11p vielonmusk 21-01-2022 15 1   Download

It has been postulated that patient’s sex impacts response to immunotherapy. Sex modulation of immunotherapy benefit, however, has not yet been explored using patient-level data, where potential confounder, as well as histologic type, can be accounted for. Here we investigated the association between sex and chemoimmunotherapy efficacy for non-small cell lung cancer (NSCLC) using a large, nation-wide dataset.

8p vielonmusk 21-01-2022 20 2   Download

Cancer cells prefer utilizing aerobic glycolysis in order to exacerbate tumor mass and maintain un-regulated proliferative rates. As a key glycolytic activator, phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) has been implicated in multiple tumor type progression.

11p vielonmusk 21-01-2022 12 1   Download

Hematopoiesis and blood diseases include leukemia and unclassified blood disorders (UBDs). Leukemia, one of the leading causes of cancer death in the world, is divided into four major types including acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML) and chronic myeloid leukemia (CML).

15p tamynhan10 24-10-2020 11 2   Download