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Chronic hepatitis C
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Hepatocellular carcinoma (HCC) is a primary tumor of the liver. The majority of HCCs are associated most frequently with chronic B or C viral hepatitis, alcohol intake or aflatoxin exposure. Cirrhosis is a strong risk factor associated with HCC.
8p
vitiki
30-01-2024
9
2
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Part 1 book "Comparative hepatitis" includes content: Hepatitis in the clinics — Treatment options, differential diagnosis of human hepatitis, comparative pathology, hepatitis B virus - Lessons learned from the virus life cycle, chronic hepatitis C - Portrait of a silent epidemic and the etiologic agent, hepatitis A infection, hepatitis E infection, bacterial infections of the liver.
171p
muasambanhan01
13-12-2023
2
1
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Hepatocellular carcinoma (HCC) has high incidence and mortality worldwide. Local ablation using radiofrequency ablation (RFA) or microwave ablation (MWA) is potentially curative for early-stage HCC with outcomes comparable to surgical resection. We explored the influence of demographic, clinical, and laboratory factors on outcomes of HCC patients receiving ablation.
14p
viangelamerkel
27-07-2022
7
3
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In particular, the IL28B gene polymorphisms have been studied and shown to have impacts on drug responses in the treatment of many diseases, such as chronic hepatitis C, chronic hepatitis B, and myeloproliferative neoplasms.
14p
meyerowitz
25-12-2021
13
0
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Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths in Africa. In Africa, the major causes of HCC include chronic infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV). Knowledge of the changes in the incidence of viral hepatitis-associated HCC over time and the factors responsible for such changes is key in informing policies for the prevention of viral hepatitis-associated HCC in Africa.
13p
vimahuateng
26-11-2021
8
0
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Intra-host hepatitis C virus (HCV) populations are genetically heterogeneous and organized in subpopulations. With the exception of blood transfusions, transmission of HCV occurs via a small number of genetic variants, the effect of which is frequently described as a bottleneck.
9p
vilarryellison
29-10-2021
9
1
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Identification of acute or recent hepatitis C virus (HCV) infections is important for detecting outbreaks and devising timely public health interventions for interruption of transmission. Epidemiological investigations and chemistry-based laboratory tests are 2 main approaches that are available for identification of acute HCV infection. However, owing to complexity, both approaches are not efficient.
10p
vilarryellison
29-10-2021
9
0
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To determine the prevalence of patient-reported joint pain among patients with human immunodeficiency virus (HIV)/chronic hepatitis C virus (HCV) coinfection, chronic HCV monoinfection, and HIV monoinfection followed in hepatology and infectious disease outpatient practices.
8p
vianttinic2711
20-04-2021
11
1
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The aim of this study was to determine the prevalence of depression and anxiety in chronic hepatitis C patients receiving pegylated interferon alpha (PegIFN) and ribavirin (RBV) therapy and to detect the possible risk factors for development of these adverse events.
10p
gaocaolon9
22-12-2020
13
1
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Since its discovery in 1989, hepatitis C virus (HCV) infection has become a major cause of chronic liver disease worldwide with 14.7% prevalence in Egypt. There is increasing body of evidence that chronic HCV infection is usually associated with several extrahepatic manifestations. Several studies have shed light on the association of autoimmune thyroiditis (ATD) and type 1 diabetes (T1D) with chronic HCV infection as both are considered to be one of the most common organ specific autoimmune disease frequently occur together.
10p
angicungduoc8
07-11-2020
11
1
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The pathophysiological overlapping between Sjorgen’s Syndrome (SS) and HCV, presence of antimuscarinic receptor type 3 (M3R) antibodies in SS, the role that M3R plays in the regulation of the heart rate, has led to the assumption that cardiovagal dysfunction in HCV patients is caused by anti-M3R antibodies elicited by HCV proteins or by their direct interaction with M3R.
13p
vioklahoma2711
19-11-2020
17
2
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The revolution of Epigenetics mechanisms including mi-RNA, DNA methylation and histone modification has drawn our attention to target Th17 cell regulatory cytokines and transcription factors which in turn will inhibit the production of interleukin 17 (IL17)- as it’s the key proinflammatory cytokine secreted by TH17 cells.
7p
nguathienthan8
20-10-2020
12
2
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HCV is a major cause of increased morbidity and mortality in patients with chronic kidney disease (CKD). Since, HCV is transmitted through blood and blood products prevalence of anti-HCV among Hemodialysis (HD) patients is consistently higher among them. Factors such as blood transfusion and frequent parenteral interventions have been shown to be associated with increased risk of HCV infection.
5p
chauchaungayxua8
03-10-2020
16
1
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The aim of this study was to investigate the mutational diversity of HCV core and NS5A regions and variation ofIL28B gene to predict virological response. Thirty HCV patients were included in this study.
17p
chauchaungayxua8
03-10-2020
11
2
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Chronic hepatitis C virus (HCV) infection remains a global health threat with 175 million carriers worldwide. Approximately 3% of the worldwide population is infected with the hepatitis C virus (HCV). Lymphoproliferative disorder (LPD) is a term that includes a wide spectrum of pathologies ranging from a minor expansion of a B-cell population (with no clinical significance) to an aggressive high-grade lymphoma. Such proliferations of B cells apparently can be triggered as a consequence of a chronic antigenic stimulation resulting from an HCV infection.
15p
trinhthamhodang1215
23-09-2020
6
1
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The acyclic retinoid, peretinoin, has been shown to be effective for suppressing hepatocellular carcinoma (HCC) recurrence after definitive treatment in a small-scale randomized clinical trial. However, little has been documented about the mechanism by which peretinoin exerts its inhibitory effects against recurrent HCC in humans in vivo.
13p
vijennie2711
29-09-2020
13
1
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Hepatitis C infection is a liver disease caused by the hepatitis C virus (HCV). It is one of the important risk factor causing acute to chronic illness in form of altered liver functions or development of chronic hepatitis, cirrhosis, hepatocellular carcinoma and liver failure.
5p
cothumenhmong7
09-09-2020
18
1
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This study was designed to investigate the impact of liver cirrhosis due to chronic hepatitis C virus (HCV) infection on the disease-free and overall survival of ovarian cancer patients undergoing a standard primary operation followed by standard chemotherapy.
7p
vimoscow2711
29-08-2020
12
1
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Hepatitis B virus (HBV) and hepatitis C virus (HCV) are the major causes of chronic hepatitis infection (CHI). This longitudinal cohort study investigated the association of CHI with hepatic and extrahepatic cancer development in Taiwan.
9p
vimale2711
25-08-2020
11
2
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Hepatitis C virus (HCV) infects many people worldwide and it is a leading cause of cirrhosis and hepatocellular carcinoma. Natural Killer (NK) cells have an important role during HCV infection as a part of innate immune responses. Three subtypes of NK cells are recognized: CD56dim CD16+ve, CD56bright CD16+ve and CD56–veCD16+ve. Natural killers T (NKT) (CD3CD16CD56+ve) cells are subsets of T lymphocytes that help in innate immune response because they can be directly cytotoxic.
13p
chauchaungayxua6
26-06-2020
21
1
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