Chronic pancreatitis

Chronic pancreatitis (CP) is a benign inflammatory disease involving the progressive and irreversible destruction of the pancreatic tissue, fibrosis and loss of exocrine and endocrine function. Clinical management of CP is also challenging because of the incomplete understanding of disease and pain pathogenesis. In Hue Central Hospital, CP is primarily treated with open drainage procedures.

7p vinatisu 29-08-2024 2 1   Download

Pancreatic ductal adenocarcinoma (PDAC), one of the most lethal malignancies, is increasing in incidence. However, the stromal reaction pathophysiology and its role in PDAC development remain unknown. We, therefore, investigated the potential role of histological chronic pancreatitis findings and chronic inflammation on surgical PDAC specimens and disease-specific survival (DSS).

12p vielonmusk 21-01-2022 14 1   Download

Diabetes mellitus is a condition of chronic increase in blood sugar, is not contagious, hereditary, caused by lack of insulin (pancreatic insulin secretion or insulin does not work not effective). Lecture Diabetes mellitus to help you know: overview of diabetes, discussion about guidelines of diabetes management, implementation in clinical practice.

75p tuoihaimuoi32 17-06-2014 64 4   Download

Humanpancreatic secretions contain twomajor trypsinogen isoforms, cationic and anionic trypsinogen, normally at a ratio of 2 : 1. Pancreatitis, pancreatic cancer and chronic alcoholism lead to a characteristic reversal of the isoform ratio, and anionic trypsinogen becomes the predominant zymogen secreted. To understand the biochemical conse-quences of these alterations, we recombinantly expressed and purified both human trypsinogens and documented characteristics of autoactivation, autocatalytic degradation and Ca 2+ -dependence....

12p fptmusic 16-04-2013 40 3   Download

Human chymotrypsin C (CTRC) plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. Mutations that abolish activity or secretion of CTRC increase the risk for chronic pancreatitis.

13p cosis54 09-12-2012 40 2   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Pancreas divisum and duodenal diverticula as two causes of acute or chronic pancreatitis that should not be overlooked: a case report

4p dauphong1 22-12-2011 48 4   Download

Viêm tụy mạn tính là sự phá hủy, xơ hoá tụy, tổn thương lan toả hoặc khu trú thành từng ô, xơ hoá và calci hoá lan toả, calci ở ống wirsung làm hẹp lòng ống tụy tạo u nang giả tụy dẫn đến làm giảm chức năng nội tiết và ngoại tiết của tụy.

7p lananhanh234 30-08-2011 78 6   Download

Efficacy of SNS in Different Disease States Efficacy studies have shown that malnourished patients undergoing major thoracoabdominal surgery benefit from SNS. Critical illness requiring ICU care including major burns, major trauma, severe sepsis, closed head injury, and severe pancreatitis [positive CT scan and Acute Physiology and Chronic Health Evaluation II (APACHE II) 10] all benefit by early SNS, as indicated by reduced mortality and morbidity. In critical illness, initiation of SNS within 24 h of injury or ICU admission is associated with a ~50% reduction in mortality.

5p konheokonmummim 03-12-2010 68 5   Download

Choledocholithiasis is the most common cause of extrahepatic cholestasis. The clinical presentation can range from mild right upper quadrant discomfort with only minimal elevations of the enzyme tests to ascending cholangitis with jaundice, sepsis, and circulatory collapse. PSC may occur with clinically important strictures limited to the extrahepatic biliary tree. In cases where there is a dominant stricture, patients can be effectively managed with serial endoscopic dilatations.

5p ongxaemnumber1 29-11-2010 59 3   Download