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Commercial drug
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Multidrug-resistant (MDR) Mycobacterium tuberculosis complex strains not detected by commercial molecular drug susceptibility testing (mDST) assays due to the RpoB I491F resistance mutation are threatening the control of MDR tuberculosis (MDR-TB) in Eswatini.
11p
vibransone
28-03-2024
3
2
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Profiling the somatic mutations of genes which may inform about tumor evolution, prognostics and treatment is becoming a standard tool in clinical oncology. Commercially available cancer gene panels rely on manually gathered cancer-related genes, in a “one-size-fits-many” solution.
9p
vioraclene
31-03-2024
3
2
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Part 1 book "Manual of commercial methods in clinical microbiology" includes content: Role of the us food and drug administration in the regulation of clinical microbiology devices; commercial blood culture systems and methods; rapid devices and instruments for the identification of aerobic bacteria; rapid devices and instruments for the identification of anaerobic bacteria; rapid antigen devices and instruments for the detection and identification of viruses; molecular tests for the identification of viruses; viral hepatitis,.... and other contents.
296p
oursky09
12-11-2023
7
2
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To compare 3 commercial knowledge bases (KBs) used for detection and avoidance of potential drug-drug interactions (DDIs) in clinical practice. Methods: Drugs in the DDI tables from First DataBank (FDB), Micromedex, and Multum were mapped to RxNorm. The KBs were compared at the clinical drug, ingredient, and DDI rule levels.
7p
visteverogers
24-06-2023
4
3
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All default electronic health record and drug reference database vendor drug-dose alerting recommendations (single dose, daily dose, dose frequency, and dose duration) were silently turned on in inpatient, outpatient, and emergency department areas for pediatric-only and nonpediatric-only populations.
6p
visteverogers
24-06-2023
8
2
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To extract drug indications from a commercial drug knowledgebase and determine to what extent drug indications can discriminate between look-alike-sound-alike (LASA) drugs. We extracted drug indications disease concepts from the MedKnowledge Indications module from First Databank Inc. (South San Francisco, CA) and associated them with drugs on the Institute for Safe Medication Practices (ISMP) list of commonly confused drug names.
13p
visteverogers
24-06-2023
3
2
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Human being has strong and historic connections with plants to fulfill food, feed, and shelter. Moreover, human uses plants as medicine for the treatment of various diseases. Plants are chemical factories for the biosynthesis of the huge number of secondary metabolites (SMs) that are directly used as a medicine or indirectly used in the development of commercial pharmaceutical drugs.
22p
lyhuyenthu
31-01-2023
6
2
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Vaginal administration is a promising route for the local treatment of infectious vaginal diseases since it can bypass the first-pass metabolism, drug interactions, and adverse effects. However, the commercial products currently available for topical vulvovaginal treatment have low acceptability and do not adequately explore this route.
11p
viginny
30-12-2022
5
2
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Robenacoxib (Onsior™) is a non-steroidal anti-inflammatory drug developed for canine and feline use for the control of pain and inflammation. It is available as both tablets and solution for injection. The objective of this study was to evaluate the safety of the interchangeable use of commercially available robenacoxib formulations when administered to cats orally using 6 mg tablets and subcutaneously using a solution for injection containing 20 mg/mL.
13p
vigandhi
23-02-2022
8
1
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Electrochemical properties of disulfiram, representative of highly significant bioactive compounds, were studied with a cyclic renewable silver amalgam film electrode (Hg(Ag)FE) using square wave cathodic stripping voltammetry (SWCSV). The influence of various factors such as pH, buffer concentration, buffer composition, and SWCSV parameters on current response was investigated. The applicability of the developed method was tested in the determination of disulfiram in the commercial formulation Anticol.
9p
langthannam
29-12-2021
13
0
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The adverse effects of high temperature stress can be alleviated by thermotolerance induced by exogenous application of plant growth regulators or by gradual application of temperature stress. Physalis peruviana L., commonly known as the Cape gooseberry, is a source of a variety of phytocompounds such as withanolides (withanone, withaferin A, and withanolide A). These withanolides are potentially high-value drug candidates because of their various pharmacological properties. The production of withanolides via traditional agriculture is commercially inadequate.
7p
tudichquannguyet
29-11-2021
14
1
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The M2 protein of the influenza A virus, responsible for flu, is a homotetramer transmembrane protein, forming a transmembrane ion channel, where His 37s act as pH sensors and Trp 41s and Asp 44s act as channel gates. Opening of this channel leads to transfer of virus RNA into the human host. Thus, blocking this transfer is an important pharmaceutical strategy to stop infection. As a result of viral drug resistance, commercially available channel inhibitors, rimantadine (RIM) and amantadine (AMA), are not as effective as they used to be.
17p
tudichquannguyet
29-11-2021
13
1
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Holostemma ada-kodien is a vulnerable medicinal species belongs to family asclepiadaceae, commonly known as Jeevanti, is being used since the ancient time, in the form of the drug Jivanthi. It has been attributed to contain numerous medicinal properties and is of very high commercial value. The tuberous roots of H. ada-kodien are used in herbal formulas.
6p
cothumenhmong9
18-01-2021
10
2
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The present study was conducted to evaluate the effect of various antimycoplasma drugs on haematological and biochemical changes in commercial broilers. Three hundred and twenty, day-old, unsexed broiler chicks of Vencobb strain were randomly allotted to 7 treatment groups with each treatment having 4 replicates and each replicate consisting of 10 birds. T1 served as negative control, T2-T7 groups were administered with Tylosin, Enrofloxacin, Taimulin, Erythromycin, Tilmicosin and Nizatidine whereas, T8 served as positive control group.
9p
caygaocaolon7
18-09-2020
16
1
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Dopamine agonists (DAs) are the first-line treatment for prolactinomas, which account for 25–30% of functioning pituitary adenomas, and bromocriptine (BRC) is the only commercially available DAs in China. However, tumors are resistant to therapy in 5–18% of patients.
10p
vialabama2711
21-09-2020
10
0
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Combination therapy, which reduces the dosage intensity of the individual drugs while increasing their efficacy, is not a novel approach for the treatment of cancer. Methylsulfonylmethane (MSM) is an organic sulfur compound shown to act against tumor cells. Tamoxifen is a commercially available therapeutic agent for breast malignancies.
16p
viamsterdam
18-09-2020
9
1
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Here various types of biosensors such as physicochemical, bioluminescent, electrochemical, opto-electric, piezoelectric, thermometric and magnetic has been deliberated to show their usefulness and applications in multiple field. Food industry requires suitable analytical methods for the safety and quality checking of foods. Chemical and biological hazards detection in foods is important to the human health.
17p
caygaocaolon6
30-07-2020
17
1
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Two commercially available microneedle rollers with a needle length of 200 μm and 300 μm were selected to examine the influence of microneedle pretreatment on the percutaneous permeation of four non-steroidal anti-inflammatory drugs (diclofenac, ibuprofen, ketoprofen, paracetamol) with different physicochemical drug characteristics in Franz-type diffusion cells.
7p
viorochimaru2711
30-05-2020
23
1
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Korean ginseng (Panax ginseng C.A. Meyer) is a highly effective medicinal plant containing ginsenosides with various pharmacological activities, whose roots are produced commercially for crude drugs.
12p
vihashirama2711
21-05-2020
18
1
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Economic impact assessment due to coccidiosis was conducted in commercial layer farms during the period from June, 2015 to January, 2016. A total of 6 poultry farms which were screened for coccidiosis, 3 layer farms (L1, L2 and L3) were found to be positive and among these 3 farms, in farm L1 and L2 no subclinical form of coccidiosis was recorded with maximum economic loss being due to mortality followed by chemotherapy and chemoprophylaxis. While in farm L3, no chemoprophylactic drug was used with maximum loss due to chemotherapy cost followed by loss in egg production and mortality.
6p
nguaconbaynhay5
16-05-2020
9
1
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