Contractile tension

Opioid induced bowel dysfunction is the most common side effect of preoperatively administrated morphine, fentanyl and its derivative. However, the influence of dezocine on intestinal mobility is rarely reported.

5p vivalletta2711 11-01-2020 12 1   Download

The effect of geteratisin (3–200 micromol/L) and 6–O–benzoylgeteratisin (10–250 micromol/L) on the contractile activity of the rat aorta smooth muscle cells (SMC) was studied. Isometric tension forces were recorded using a force transducer FT–03 (Grass Instrument Co., USA). In the experiments it was revealed that vasorelaxant effect of heteratisine is mainly associated with the blockade of Ca2+L–channel, receptor–operated Ca2+ –channels (ROCC), and store–operated Ca2+–channels (SOCC).

7p quenchua2 15-12-2019 8 0   Download