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CYP genes
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The allele frequencies and phenotypic distributions of the five important CYP genes in the Vietnamese population are similar to those in East Asia while significantly different from other populations. In silico analysis also provided consistent results with previous experimental studies.
16p
vimulcahy
18-09-2023
5
3
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The cytochrome P450 monooxygenases (CYP450, CYP, P450) catalyze numerous monooxygenation/ hydroxylation reactions in biochemical pathways. Although CYP superfamily has been systematically studied in a few species, the genome-scale research about it in rice has not been done.
18p
vibeauty
23-10-2021
8
0
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We evaluated the role of CYP3A5, ABCB1 and SXR gene polymorphisms in the occurrence of acute kidney rejection in a cohort of pediatric renal transplant recipients.
7p
viorochimaru2711
29-05-2020
10
1
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Cyclophilins (CYPs) belong to the immunophilin superfamily, and have peptidyl-prolyl cis-trans isomerase (PPIase) activity. PPIase catalyzes cis- and trans-rotamer interconversion of the peptidyl-prolyl amide bond of peptides, a rate-limiting step in protein folding.
11p
viminato2711
22-05-2020
9
1
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Cytochrome P450s (CYPs) are one of the largest distributed enzymes, which catalyze more than 20 different reactions. At present, there has been an increasing realization of the power of P450 biocatalysts for the industrial synthesis of pharmaceuticals, agrochemicals, bulk chemicals, food ingredient, etc.
5p
viaphrodite2711
15-10-2019
10
0
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The heme of cytochrome P460 ofNitrosomonas europaea, which is covalently crosslinked to two cysteines of the polypeptideaswithallc-type cytochromes, has anadditional novel covalent crosslink to lysine 70 of the polypeptide [Arciero,D.M.&Hooper,A.B. (1997)FEBSLett.410, 457– 460]. The protein can catalyze the oxidation of hydroxyl-amine. The gene for this protein,cyp,wasexpressedin Pseudomonas aeruginosastrain PAOlacI, resulting in for-mation of a holo-cytochrome P460 which closely resembled native cytochrome P460 purified fromN. ...
7p
fptmusic
16-04-2013
46
3
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The present study aimed to determine the role of Kupffer cells (KCs) in cytochrome P450 (CYP) isozyme activity and the expression of its gene during polymicrobial sepsis. For ablation of KCs, rats were pretreated with gadolinium chloride (GdCl3 ) at 48 and 24 h before cecal ligation and punc-ture (CLP). The depletion of KCs was confirmed by measuring the mRNA level of the KC marker gene CD163.
11p
cosis54
05-01-2013
40
2
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