Development of methods

Valsartan, an angiotensin blocker, is often combined with amlodipine (a calcium channel antagonist) in the current treatment of hypertension. There is a generic brand-name drug Exforge® which has been proven to be clinically effective. However, its price is high, making it quite difficult to access, especially in low- and middle-income countries. Therefore, research and development of generic drugs is essential.

7p vinara 11-01-2025 0 0   Download

The research focuses on the composition of a hard capsule formula containing the extracts of Houttuynia cordata, Morus alba, and Carica papaya as well as the development of testing standards for prepared hard capsules. Materials and methods: the ratio of adsorbents and fillers in the formula was investigated so that the granules had low moisture, a suitable flow rate, and the appropriate apparent density for packaging.

9p vinara 11-01-2025 0 0   Download

One of the crucial methods for lowering hospital infections is air disinfection. Because the airborne contagion environment is difficult to control, the development of effective air disinfectants is critical to maintaining a safe air environment and preventing respiratory infections. At the Hospital of Can Tho University of Medicine and Pharmacy.

7p vinara 11-01-2025 0 0   Download

Drug resistant tuberculosis (DR-TB) remains a global health problem. The diagnosis, treatment, and management of DR-TB are the major challenges to Vietnam National Tuberculosis Control Program. One of the most important solutions for overcoming this problem is developing reliable and low-cost methods, which have been proposed to Drug Susceptibility Testing (DST) to detect drug resistant tuberculosis.

6p viharuno 03-01-2025 11 2   Download

The combination of hydrochlorothiazide (HCT), amlodipine besylate (AML) and olmesartan medoxomil (OLM) is highly effective in treating hypertension. Currently, Vietnamese Pharmacopoeia V and other reference pharmacopoeias do not have a procedure for the simultaneous quantification of these three ingredients. To develop and validate a procedure for simultaneous determination of HCT, AML and OLM in tablets by HPLC method.

11p viharuno 03-01-2025 1 1   Download

Drug-resistant Tuberculosis (DR-TB) is challenging public health problem in countries with high tuberculosis prevalence and limited resources. Developing and applying the most appropriate and effective methods for diagnosing DR-TB from clinical samples is necessary, allowing a more rapid detection method for large-scale screening.

7p viharuno 03-01-2025 3 1   Download

Objectives: (1) Developing a capillary zone electrophoresis method for determining simultaneously paracetamol and diclofenac in pharmaceutical formulations (2) Applying this method on the products circulated on the market. Materials and methods: Paracetamol and diclofenac in Zengesic and Ripaigesic film-coated tablets were used in this research.

7p viuchiha 03-01-2025 2 2   Download

Metformin is an oral antidiabetic drug from the biguanide class and it is the first-line drug chosen for the treatment of type 2 diabetes. This is a drug on the list of pharmaceutical substances required to report bioequivalence study data when registering the drug. Objectives: (1) To develope a capillary zone electrophoresis method for determining metformin hydrochloride in human plasma. (2) To validate the method.

10p viuchiha 03-01-2025 3 1   Download

The article uses analytical and synthetic research methods and methods of collecting secondary data for clarification Current status of publishing activities in Ho Chi Minh City and Propose solutions to improve the quality of publishing activities in the City in the near future.

11p gaupanda068 02-01-2025 2 2   Download

This research aims at investigating the effects of implementing teaching grammar through context on the development of students’ language competence. It also aims to identify students’ problems and their learning styles with the expectation that this new method will help them to get the hang of perceiving the rules of new grammar structures and providing accuracy in the target language.

20p caphesuadathemmuoi 11-11-2021 16 3   Download

In this thesis, I have developed a low-cost, simple and one-step approach to synthesize MnO2/graphene composite with enhanced electrochemical performance. MnO2/graphene composite was prepared via a plasma-assisted electrochemical exfoliation method with an electrolyte solution made of KMnO4 precursor.

60p nienniennhuy77 31-12-2024 3 1   Download

The study aimed to assess the current implementation of the Translation Internship Module at the faculty of English, Hanoi Open University, so as to propose methods to evaluate the Translation Internship module in accordance with the orientation of developing the capacity to meet the course learning outcome.

9p vibenya 31-12-2024 1 1   Download

Greenwashing, defined as the dissemination of inaccurate or misleading information regarding the environmental performance of products, services, or brands, has become increasingly prevalent in the construction industry. This study examines the extent and consequences of greenwashing in the sector, focusing on how exaggerated sustainability claims influence stakeholder trust and decision-making.

5p vibenya 31-12-2024 2 1   Download

In this study, a new method for analyzing safety factor (Fs) of natural slopes was developed. Rigid-plastic constitutive equation for soil materials and a slope stability analysis framework were formulated to account for both soil properties and slope geometry (slope angle β and slope height H).

6p vibenya 31-12-2024 3 1   Download

The authors develop a system of differential equations describing the motion of the structural system equipped with DFP bearings. The Runge-Kutta numerical method, specifically the ode15s function in MATLAB, was used to solve these equations. The results of the calculations provide a comparison of the damping efficiency of the structural system with and without the use of DFP bearings, assessing the effectiveness of vibration isolation during an earthquake, with three components X, Y, and vertical considered.

5p vibenya 31-12-2024 7 1   Download

This paper introduces a verification model that integrates Colored Petri Nets (CPN) into the PDA development lifecycle to improve process verification. By converting BPMN models into CPN, the method allows for early detection of errors such as deadlocks and inconsistencies.

6p vibenya 31-12-2024 4 2   Download

Interpreting, like playing chess, is a game of problem solving, evaluation, critical thinking, intuition and forecasting. Every game is different and each game is a challenge, which requires interpreters, to unceasingly develop knowledge and experience. It is disciplined study and repeated practice of many techniques and skills that bring victory to the interpreter. Apart from basic requirements of language mastery and culture sensitivity, there are quite a few skills that need to be acquired for successful interpreting. One of them is note-taking skill....

61p hattieubenho2009 13-11-2012 225 76   Download

This thesis describes a quality method that was developed to measure the quality of a tool or technique based on the results it produces. Based on the results of these measurements on current carving tools, a number of areas were identified that could be improved. A new carving framework was developed to address these points of improvements, and its results were tested using the previously developed quality method. The new carving framework achieved significantly better results on all identified improvement areas.

110p longtimenosee02 03-01-2024 11 5   Download

This research presents a method for the identification of hazardous situations on the freeways as well as the hazard mitigation system based on the identification. The hazard identification is done using a crash risk probability model and based on the identification, mitigation strategy is employed to reduce the effect of the hazard. For this study, about 18 km long section of Eastern Freeway in Melbourne, Australia is selected as a test bed.

125p runthenight05 01-03-2023 8 3   Download

The prediction of the expected long-term performance of concrete exposed to sewage and similar materials can be difficult as it is affected by a large number of parameters. In addition, the deterioration process in concrete is generally slow. The focus of the study was to ascertain the life expectancy of concrete septic tanks located in rural Victoria. In developing the accelerated test method, ASTM C 192, ASTM C 452, ASTM C 1293 and ASTM C 109 standard procedures were adopted wherever possible.

172p runthenight05 01-03-2023 9 3   Download