Diagnosis of chikungunya by

Vector borne diseases have gained importance in recent decade due to the increasing frequency of sporadic episodes occurring in both endemic and non-endemic areas. The similar clinical presentation and the acute febrile nature results in misdiagnosis often and increases the risk of transmission and morbidity in the vulnerable populations. A study was undertaken to check the prevalence of Chikungunya virus among the febrile patients presenting with body ache or mayalgia between June 2014 and July 2015.

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Chikungunya fever is caused by an arbovirus belonging to the Alphavirus genus of the Togaviridae family. It was first isolated in the Newala district of Tanzania in 1952–1953. Chikungunya virus is no stranger to the Indian subcontinent. It was first reported from Calcutta (Kolkata now) and was responsible for about 200 mortality3 . Since then several outbreaks of Chikungunya fever have been documented from different parts of India. Chikungunya virus is transmitted to humans by Aedes mosquitoes.

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Health care providers lacking proper diagnostic tools are usually unable to determine specific etiologies, often diagnosing patients with acute undifferentiated febrile illness (AUFI) presumptively based on clinical features and assumptions regarding circulating pathogens. Acute fever can be potentially fatal if the etiology is not recognized and treated appropriately. A cross-sectional study was conducted in a tertiary care hospital, Bengaluru, from July-December 2018. Blood was collected from patients with acute fever for peripheral smear, serological tests.

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Rickettsial diseases are an important cause of undifferentiated acute febrile illness. The lack of classical manifestations can make their diagnosis difficult. Even though the diseases are endemic in India, they are less reported from New Delhi and surrounding regions. Aim is to estimate the seropositivity of Rickettsial infections in cases of undifferentiated acute febrile illness from a tertiary care hospital in New Delhi and to analyze their clinical profile. This prospective observational study was conducted from November 2016 to March 2018.

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