![](images/graphics/blank.gif)
Disease-associated gene
-
Classifying pathogenicity of missense variants represents a major challenge in clinical practice during the diagnoses of rare and genetic heterogeneous neurodevelopmental disorders (NDDs). While orthologous gene conservation is commonly employed in variant annotation, approximately 80% of known disease-associated genes belong to gene families.
12p
vibransone
28-03-2024
3
2
Download
-
Expression quantitative trait loci (eQTL) databases represent a valuable resource to link diseaseassociated SNPs to specific candidate genes whose gene expression is significantly modulated by the SNP under investigation.
16p
vioraclene
31-03-2024
4
2
Download
-
The driver tissues or cell types in which susceptibility genes initiate diseases remain elusive. We develop a unified framework to detect the causal tissues of complex diseases or traits according to selective expression of diseaseassociated genes in genome-wide association studies (GWASs).
19p
vielonmusk
30-01-2022
12
0
Download
-
With the global spread of multi drug resistance in pathogenic microbes, infectious diseases emerge as a key public health concern of the recent time. Identification of host genes associated with infectious diseases will improve our understanding about the mechanisms behind their development and help to identify novel therapeutic targets.
12p
vicolorado2711
23-10-2020
14
2
Download
-
The misregulation of microRNA (miRNA) has been shown to cause diseases. Recently, we have proposed a computational method based on a random walk framework on a miRNA-target gene network to predict disease-associated miRNAs.
13p
vicolorado2711
22-10-2020
5
0
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)