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Ectopically overexpressed
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Excessive accumulation of salts is one of the most important factors affecting the production quality of plants. The difficulty to develop salt stress tolerant crops has prevented the security of the global food system. The classical crop breeding approach that uses random mutagenesis/recombination is time-consuming in the face of an ever-increasing human population and extreme weather pattern shifts.
10p
tudichquannguyet
29-11-2021
21
1
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CHCHD2 was identified a novel cell migration-promoting gene, which could promote cell migration and altered cell adhesion when ectopically overexpressed in NIH3T3 fibroblasts, and it was identified as a protein necessary for OxPhos function as well. However, the clinic relevance of CHCHD2 expression in NSCLC remains unclear.
11p
vimaine2711
26-03-2021
8
2
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Human Hematopoietic Signal peptide-containing Secreted 1 (hHSS1) is a truly novel protein, defining a new class of secreted factors. We have previously reported that ectopic overexpression of hHSS1 has a negative modulatory effect on cell proliferation and tumorigenesis in glioblastoma model systems.
17p
vilisa271
22-09-2020
13
1
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Abstract To overcome loss of stem-like properties and spontaneous differentiation those hinder the expansion and application of human mesenchymal stem cells (hMSCs), we have clonally isolated permanent and stable human MSC lines by ectopic overexpression of primary cell cultures of hMSCs with HPV 16 E6E7 and human telomerase reverse transcriptase (hTERT) genes. These cells were found to have a differentiation potential far beyond the ordinary hMSCs. They expressed trophoectoderm and germline specific markers upon differentiation with BMP4 and retinoic acid, respectively.
13p
toshiba23
18-11-2011
53
3
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