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Eliciting response
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Traditional nanodrug delivery systems have some limitations, such as eliciting immune responses and inaccuracy in targeting tumor microenvironments. Targeted drugs (Sorafenib, Sora) nanometers (hollow mesoporous silicon, HMSN) were designed, and then coated with platelet membranes to form aPD-1-PLTM-HMSNs@Sora to enhance the precision of drug delivery systems to the tumor microenvironment, so that more effective immunotherapy was achieved.
12p
vikoch
27-06-2024
1
1
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Picking and packing is the one of the main principle action in a distribution centre. Picking and packing action ensures the right product at the right quantity reaches the right customer. As such, this study is purported to recognize the issues related to picking and packing error and to know how to overcome it. The study was conducted using a semi-structured interview to elicit response concerning picking and packing issues and error.
7p
longtimenosee10
26-04-2024
4
1
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Immune checkpoint blockade therapy can elicit robust and durable responses in a variety of cancer types. While many patients do not respond, recent reports highlight a distinct group of patients whose tumors undergo rapid growth, leading to progressive disease and poor outcome.
3p
vibransone
28-03-2024
2
2
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The resurgence of immune therapies in cancer medicine has elicited a corresponding interest in understanding the basis of patient response or resistance to these treatments. One aspect of patient response clearly lies in the genomic alterations that are associated with cancer onset and progression, including those that contribute to genomic instability and the resulting creation of novel peptide sequences that may present as neoantigens.
12p
vibransone
28-03-2024
6
2
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Preclinical studies and early clinical trials have shown that targeting cancer neoantigens is a promising approach towards the development of personalized cancer immunotherapies. DNA vaccines can be rapidly and efficiently manufactured and can integrate multiple neoantigens simultaneously.
13p
vibransone
28-03-2024
7
2
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Ebook "Composting for sustainable agriculture (Sustainable development and biodiversity, Volume 3)" will comprised various chapters on the role of beneficial bacteria in the composting process. The application is depicted to achieve the attainable productivity besides, in disease management and suppressiveness of organisms of phytopathogenic in nature. Significance of the compost elicits certain responses e.g. soil reclamation, soil fertility, soil health and disease management exhibit due to quality compost amendment in soil.
295p
manmanthanhla0201
26-02-2024
2
1
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Cancer-testis antigens (CTAs) have emerged as potential clinical biomarkers targeting immunotherapy. KK-LC-1 is a member of CTAs, which has been demonstrated in a variety of tumors tissues and been found to elicit immune responses in cancer patients.
11p
vimichaelfaraday
28-12-2023
3
3
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To describe nurses’ preferences for the design of a probability-based clinical decision support (PB-CDS) tool for in-hospital clinical deterioration. Methods: A convenience sample of bedside nurses, charge nurses, and rapid response nurses (n ¼ 20) from adult and pediatric hospitals completed participatory design sessions with researchers in a simulation laboratory to elicit preferred design considerations for a PB-CDS tool.
9p
visteverogers
24-06-2023
8
3
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This study aims at exploring the questioning strategies used by teachers in the reading classes through a case study, where three classes of Reading (by one teacher who voluntarily joined in the study) were audio-recorded and observed. The teacher’s questions (and classroom interaction) were transcribed and categorized.
17p
vispiderman
15-06-2023
4
3
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Therapeutic antibodies can elicit an immune response through different mechanisms, either cell independent via complement activation (CDC) or through activation of immune-effector cells (such as macrophages and NK cells).
9p
viginny
23-12-2022
6
3
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The recognition of microbe-associated molecular patterns during infection is central to the mounting of an effective immune response. In spite of their importance, it remains difficult to identify these molecules and the host receptors required for their perception, ultimately limiting our understanding of the role of these molecules in the evolution of host-pathogen relationships.
15p
viaristotle
29-01-2022
6
0
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The bacillus Calmette-Guérin (BCG) vaccine protects against tuberculosis and heterologous infections but elicits high inter-individual variation in specific and nonspecific, or trained, immune responses. While the gut microbiome is increasingly recognized as an important modulator of vaccine responses and immunity in general, its potential role in BCG-induced protection is largely unknown.
22p
viarchimedes
26-01-2022
12
0
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Influenza is a severe respiratory illness that continually threatens global health. It has been widely known that gut microbiota modulates the host response to protect against influenza infection, but mechanistic details remain largely unknown.
26p
viarchimedes
26-01-2022
11
1
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This study aims to investigate pragmatic transfer among Vietnamese learners of English as a foreign language (EFL). It examines the speech act of apologizing in American English and Vietnamese focusing on pragmatic transfer. A discourse completion task (DCT) was used to elicit apology responses from four groups of participants: 18 native speakers of American English (Es), 20 native speakers of Vietnamese (Vs), 20 Vietnamese elementary learners of English (VEEs) and 20 Vietnamese advanced learners of English (VEAs).
14p
viwilliamleiding
04-12-2021
18
5
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Lecture Strategic Human Resource Management: Slade present the content effective use of team-based systems, working groups versus teams, common team responsibilities, costs/benefits of using teams benefits costs, team development,...
19p
bachtudu
30-09-2021
16
1
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Stress refers to the perceived or actual threat on physical and/or psychological homeostasis of the human body. Disrupted homeostasis elicits the so called “stress response”, meaning the activation of central and peripheral neuroendocrine mechanisms responsible for various adaptive responses and behaviors. PSS was originally developed as a 14-item scale that assess the perception of stressful experiences by asking the respondent to rate the frequency of his/her feelings and thoughts related to events and situations that occurred over the previous month.
6p
trinhthamhodang11
27-04-2021
19
3
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CD4+ T-cell epitopes play a crucial role in eliciting vigorous protective immune responses during peptide (epitope)-based vaccination. The prediction of these epitopes focuses on the peptide binding process by MHC class II proteins. The ability to account for MHC class II polymorphism is critical for epitope-based vaccine design tools, as different allelic variants can have different peptide repertoires.
11p
viwyoming2711
16-12-2020
20
1
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In Japan, transarterial infusion chemotherapy using cisplatin (CDDP-TAI) is frequently used for advanced hepatocellular carcinoma (HCC). Moreover, oral chemotherapy with S-1, an oral fluoropyrimidine derivative, has also elicited promising responses in HCC patients.
6p
virose2711
24-09-2020
13
0
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Cyclophosphamide treatment on a six-day repeating metronomic schedule induces a dramatic, innate immune cell-dependent regression of implanted gliomas. However, little is known about the underlying mechanisms whereby metronomic cyclophosphamide induces innate immune cell mobilization and recruitment, or about the role of DNA damage and cell stress response pathways in eliciting the immune responses linked to tumor regression.
21p
vialabama2711
21-09-2020
18
1
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Platinum-based systemic chemotherapy is the treatment of choice for patients with advanced urothelial carcinoma (UC). Although no chemotherapeutic regimen is established as a second-line therapy, recent studies reported that methotrexate, vinblastine, Adriamycin and cisplatin (MVAC) elicited a significant response in patients who failed gemcitabine and platinum (GP) chemotherapy.
8p
vimoscow2711
29-08-2020
69
2
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