Empirical therapy
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Antimicrobial-resistant (AMR) Neisseria gonorrhoeae is an urgent threat to public health, as strains resistant to at least one of the two last-line antibiotics used in empiric therapy of gonorrhoea, ceftriaxone and azithromycin, have spread internationally.
22p vibransone 28-03-2024 7 2 Download
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Allergic rhinitis is the most common allergic disease encountered in a primary care setting. Diagnosis is often made clinically based on response to empiric therapy. However, with long-term treatment failure and/or atypical disease presentation, a differential diagnosis should be considered.
7p vilazada 31-01-2024 6 2 Download
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The Gram stain can be used to direct initial empiric antimicrobial therapy when complete culture is not available. This rapid test could prevent the initiation of inappropriate therapy and adverse outcomes. However, several studies have attempted to determine the value of the Gram stain in the diagnosis and therapy of bacterial infection in different populations of patients with ventilator-associated pneumonia (VAP) with conflicting results.
5p viisaacnewton 26-04-2022 10 1 Download
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Cancer of unknown primary (CUP) is usually treated with nonselective and empirical chemotherapy; however, its prognosis is generally poor, with a median survival of less than a year. Thus, clinicians eagerly await the development of more effective treatment strategies.
5p vichaeng2711 29-04-2021 9 3 Download
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Most international guidelines recommend empirical therapy for community-acquired pneumonia (CAP) to be based on site of care. Some patients with severe CAP are managed in general wards because of limited intensive care unit (ICU) bed or because of unrecognition of the pneumonia severity.
10p vimaine2711 26-03-2021 10 2 Download
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Evidence-based interventions are needed to reduce depression among adolescents in low- and middle-income countries (LMICs). One approach could be cultural adaptation of psychological therapies developed in high-income countries.
15p vigeorgia2711 30-11-2020 22 1 Download
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The objective of this study was to determine the causative bacteria and pattern of susceptibility to antibiotics in NICU of a tertiary care center, which in turn may help in implementation of empirical therapy. This prospective study was carried out in the department of microbiology, Govt. medical college Raigarh (c.g.) during Jun 2016- Jun 2017.
5p angicungduoc8 07-11-2020 20 2 Download
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The present study was designed to evaluate the profile of aerobic pyogenic bacteria along with their susceptibility to antibiotics and aims to bridge the gap in the knowledge and also to provide the clinician with the tools to provide safe and effective empirical therapy.
6p cothumenhmong7 09-09-2020 20 1 Download
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Among the other 12 inpatient MRSA isolates which had the pvl gene, nine were sensitive to most of the non- beta lactam antibiotics, whereas remaining three were resistant to most of the antibiotics except vancomycin and linezolid. The presence of pvl gene can no longer be used to discriminate between CA-MRSA and HA-MRSA.
5p kequaidan7 01-09-2020 12 2 Download
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Neonatal septicemia is a clinically diagnosed condition having diverse etiology and changing antibiotic sensitivity pattern. The knowledge of common bacterial agents causing septicemia and their antibiogram is useful in deciding empirical antimicrobial therapy. The neonatal blood cultures were studied to know the bacterial species and their antibiotic sensitivity pattern. Aim of the study is to evaluate sensitivity pattern of bacterial isolates causing neonatal septicemia and to know clinical outcome of the cases.
9p angicungduoc6 20-07-2020 13 1 Download
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Mechanical ventilation is a life-saving procedure, but it is associated with a high risk of acquiring respiratory infections. Hence to prevent it and initiate empirical antimicrobial therapy, knowledge of microbial profile and their local antimicrobial sensitivity pattern are essential. A prospective analytical study of Endotracheal tube (ETT) aspirates of mechanically ventilated patients in Intensive Care Unit (ICU) was done over a period of six months (Dec2015-May2016).
5p chauchaungayxua6 26-06-2020 18 3 Download
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A brief study was carried on forty Staphylococcus aureus isolates from Bovine milk from Ludhiana, Punjab, India for detecting the antibiotic resistance profile using E-strips and genotypically targeting various antibiotic resistance genes. The antibiotics used for phenotypic resistance detection were Penicillin, Gentamicin, Erythromycin, Clindamycin, Tetracycline, Chloramphenicol, Ciprofloxacin, Trimethoprim-sulphamethoxazole, Oxacillin, Vancomycin and Amoxyclav.
14p nguaconbaynhay5 16-05-2020 6 0 Download
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Urinary tract infection (UTI) is considered as the most common bacterial infectious disease seen among the pediatric patients. Pediatric urinary tract infections are associated with high morbidity and long term complications like renal scaring, hypertension and chronic renal failure The epidemiology of UTI during childhood varies by age, gender and other factors (Bickerton and Ducket, 1985). Most commonly bacteria causes of UTI in children are members of Enterobacteriaceae, particularly uropathogenic strains of E. coli and Klebsiella spp.
11p nguaconbaynhay5 11-05-2020 20 1 Download
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Urinary tract infections are the commonest infectious disease, seeking medical consultation and antibiotic therapy worldwide. Klebsiella pneumonia is among the most common uropathogen responsible for recurrent infections and it antimicrobial susceptibility to commonly prescribed drugs vary significantly in different regions. Hence, the objective was to analyze the local etiology and antimicrobial susceptibility pattern of urinary K. pneumonia, to optimize the rational empirical therapy.
5p nguathienthan4 18-04-2020 26 1 Download
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Sepsis in modern surgery continues to be a significant problem for healthcare practitioners across the globe.1 Since initial antimicrobial therapy usually remains empiric; the knowledge of prevailing susceptibility patterns at individual institutions is a must. To determine the etiology of surgical site infections (SSI) in patients admitted to a tertiary care teaching hospital, study its antibiogram and the prevalence of ESBL. 200 patients who developed SSI in a teaching hospital during a period of one year were prospectively studied.
8p kethamoi4 16-04-2020 15 0 Download
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Neonatal sepsis is defined as a bacterial infection of the blood in an infant younger than 4 weeks of age. Blood cultures remain the mainstay of laboratory diagnosis of bloodstream infections (BSIs) in infants. The knowledge of bacteriological profile and its antibiotic sensitivity patterns is of immense help in saving lives of neonates with septicaemia.
12p caygaocaolon4 04-04-2020 26 2 Download
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Pulmonary fungal infections are common potentially life-threatening conditions in immuno-compromised patients. Diagnosis represents a challenge due to the non-specific clinical manifestations. Empirical use of anti-fungal drug therapy has been a burden for years due to high cost and drug toxicity. This study was designed to determine the presence of Candida chest infection in immuno-compromised patients in Tanta University Hospitals. A total of 150 patients with chest infection were selected during the period from June 2015 till June 2017.
9p trinhthamhodang4 22-03-2020 12 0 Download
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Urinary tract infection (UTI) is one of the most common bacterial infections in humans after respiratory tract infection. E.coli remains the leading uropathogen being responsible for UTI. The aim of the study is to assess the resistance pattern of E.coli causing UTI to commonly used antibiotics, so as to aid the clinician in changing the appropriate antimicrobial empirical therapy. E.coli isolated from urine samples were identified by conventional biochemical test. Antimicrobial susceptibility test was done by Kirby–Bauer disc diffusion method on Mueller–Hinton agar.
6p trinhthamhodang4 22-03-2020 20 1 Download
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Prompt initiation of empiric therapy is common practice in case of suspected meningitis or encephalitis. However, in children the most common pathogens are viruses that usually do not require and are not covered by the applied anti-infective treatment. Novel multiplex PCR (mPCR) panels provide rapid on-site diagnostic testing for a variety of pathogens.
10p vivalanbo2711 19-03-2020 11 2 Download
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Blood stream infections are mainly caused by multi drug resistant organisms which more likely prolong the hospital stay and leads to increased health care costs. Hence, early diagnosis and treatment with appropriate antibiotics is the only way to treat bacteraemia. To study the bacteriological profile of the organisms causing septicaemia and their antibiotic resistance patterns to guide the clinicians to initiate the empirical therapy. Blood samples were collected aseptically from patients before taking any antibiotics.
7p cothumenhmong3 22-02-2020 16 0 Download