Endocrine cancers
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In recent years, breast cancer (BC) incidence and mortality have been the highest in females. Menopause-like syndrome (MLS), arising from hypoestrogenism caused by endocrine therapy, signifcantly afects the quality of life for females. Traditional Chinese Medicine (TCM) has advantages in ameliorating MLS, but the efficacy of TCM in patients with BC has not been systematically evaluated.
19p vishanshan 27-06-2024 1 1 Download
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This research designeded to: 1. Analyze the efficacy and safety of Palbociclib treatment in HR-positive and HER2-negative (HR+/HER2-) metastatic breast cancer(MBC) patients. 2. Establish and validate a nomogram model for predicting the progression-free survival (PFS) rates of 6 months, 12 months, and 18 months in HR+/HER2- MBC patients after receiving Palbociclib plus endocrine therapy (ET).
13p vishanshan 27-06-2024 2 1 Download
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This book provides in-depth practical advice on how to manage children with endocrine conditions that may benefit from surgery. It is more detailed than general pediatric surgery texts and more surgically oriented than endocrinology texts. The first section is devoted to the thyroid and parathyroid, with detailed discussion of thyroid nodules, thyroid cancer, hyperthyroidism, hyperparathyroidism, and multiple endocrine neoplasia;...
451p vimeyers 29-05-2024 3 2 Download
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Ebook "Hormonal carcinogenesis V" information gathered from cell-free systems, cell cultures, animal models, and human studies, together will (1) provide important insights to our understanding of hormonal cancer causation, development, and prevention; (2) be the primary objective of these Symposia.
647p ladongphongthanh1008 22-04-2024 2 1 Download
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Ebook Breast cancer management for surgeons: Part 2 includes content: Speciic autologous flap techniques, goldilocks procedure, nipple reconstruction, complications of breast surgery and their management, adjuvant endocrine therapy, adjuvant chemotherapy, hereditary breast cancer,… and other contents. Invite you to consult the details.
394p longtimenosee03 01-02-2024 2 0 Download
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Melanoma develops in the cells that produce melanin; ocular melanoma accounts for 3–4% of all malignant melanomas. Thyroid tumors are the most common endocrine neoplasms, with more than 95% of cases arising from follicular cell origin. Previous studies have reported associations between malignant melanoma and a wide variety of malignancies.
7p vigojek 02-02-2024 2 1 Download
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Part 2 book "Withrow and MacEwen's small animal clinical oncology" includes content: Melanoma; mast cell tumors; soft tissue sarcomas; cancer of the gastrointestinal tract; tumors of the respiratory system; tumors of the skeletal system; tumors of the endocrine system; tumors of the female reproductive system; tumors of the mammary gland; tumors of the male reproductive system; tumors of the urinary system; tumors of the nervous system; ocular tumors; hematopoietic tumors; miscellaneous tumors.
478p muasambanhan05 22-01-2024 6 2 Download
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Despite benefits of endocrine therapy (ET) for patients with hormone-receptor (HR)-positive breast cancer, many patients do not initiate or discontinue ET against recommendations.
12p vimichaelfaraday 28-12-2023 5 3 Download
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The adjuvant treatment with Aromatase Inhibitor (AI) is considered standard of care for postmenopausal breast cancer (BC) women with hormone receptor-positive (HR+), however, it often causes adverse effects such as cancer-related fatigue (CRF).
20p vialfrednobel 23-12-2023 4 3 Download
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Tamoxifen is one of the fundamental pillars of adjuvant endocrine therapy for hormone receptor-positive breast cancer; however, 30–50% of patients receiving tamoxifen experience tumor relapse. This study aimed at determining the frequencies of the most clinically relevant CYP2D6 alleles and evaluating their impact on the respon‑siveness to tamoxifen in a cohort of Syrian breast cancer patients.
11p vialfrednobel 23-12-2023 6 3 Download
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Endocrine therapy is frequently administered in patients with hormone dependent (HR+) metastatic endometrial cancer. The aim of this study was to explore the incidence and clinical relevance of circulating ESR1 mutations in patients treated by AI or megestrol acetate (M) for advanced endometrial carcinoma.
9p vialfrednobel 23-12-2023 4 3 Download
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To determine the frequency of H1047R mutation on exon 20 PIK3CA gene in the plasma of hormone recepter positive (HR+) breast cancer (BC) women and its relationship with clinical characteristics of these patients. Subjects: Plasma was separated from venous blood of 141 female HR+ BC patients, have been treating at 108 Military Central Hospital from June 2021 to June 2023.
9p vigeorge 06-12-2023 2 2 Download
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Part 2 book "Clinical equine oncology" includes content: Approach to the suspected or confirmed cancer case; tumours of the alimentary tract and abdominal cavity; tumours of the upper and lower respiratory tract; tumours of the cardiovascular system; tumours of the skin; tumours of the endocrine and neuroendocrine systems; tumours of nerves and nervous tissue; tumours of the eye; tumours of the male and female reproductive systems and mammary gland; tumours of the urinary tract; tumours of the musculoskeletal system.
288p muasambanhan01 11-12-2023 9 2 Download
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Part 1 book "Study guide for understanding pathophysiology" includes content: The cell, mechanisms of self defense, cellular proliferation - cancer, the neurologic system, the endocrine system, the hematologic system.
163p oursky09 12-11-2023 3 1 Download
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To study the stiffness characteristics of benign and malignant thyroid nodules on elastography ultrasound and the evaluation of elastography ultrasound in the diagnosis of thyroid cancer. Subject and method: This study included 535 patients with 557 thyroid nodules confirmed by histopathology, from September 2019 to August 2020.
8p vishekhar 01-11-2023 2 0 Download
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Rearranged during transfection (RET) tyrosine kinase signaling has been previously implicated in endocrine resistant breast cancer, however the mechanism by which this signaling cascade promotes resistance is currently not well described.
14p vischultz 20-10-2023 3 1 Download
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Real-world data of Palbociclib are insufficient in China. This study aimed to investigate the treatment pattern and real-world outcomes in hormone receptor positive and human epidermal growth factor 2 receptor negative (HR+/HER2-) metastatic breast cancer (MBC) patients treated with Palbociclib in the northwest of China.
13p vischultz 20-10-2023 3 1 Download
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This retrospective study explored the relationship between hormone receptor (HR), human epidermal growth factor receptor 2 (HER2) status, and bone involvement in the first distant metastases (DM) of Chinese breast cancer (BC) patients who lacked the HER2 targeted therapy.
9p vischultz 20-10-2023 3 1 Download
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There is no standard treatment recommended at category 1 level in international guidelines for subsequent therapy after cyclin-dependent kinase 4/6 inhibitor (CDK4/6) based therapy. We aimed to evaluate which subsequent treatment oncologists prefer in patients with disease progression under CDKi.
10p vischultz 20-10-2023 3 1 Download
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Endocrine-resistant breast cancers have elevated expression of XBP1, where it drives endocrine resistance by controlling the expression of its target genes. Despite the in-depth understanding of the biological functions of XBP1 in ER-positive breast cancer, efectors of endocrine resistance downstream of XBP1 are poorly understood. The aim of this study was to identify the XBP1-regulated genes contributing to endocrine resistance in breast cancer.
16p vischultz 20-10-2023 1 1 Download