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Endogenous factors
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Long nonconding RNAs (lncRNAs) have been found to be a vital regulatory factor in the development process of human cancer, and could regarded as diagnostic or prognostic biomarkers for human cancers. Here, we aim to confirm the expression and molecular mechanism of RP11-171K16.5 (lnc171) in hepatocellular carcinoma (HCC).
13p
vishanshan
27-06-2024
1
1
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Dyslipidemia is one of the popular issues in developed countries and an increasing trend in developing countries. It is a major risk factor for cardiovascular disease, hypertension and diabetes. Polyherbal formulations have been used to treat dyslipidemia for many years. This study was designed to evaluate the effects of SAGYDI (SAD) on endogenous dyslipidemia experimental animal model.
8p
vicarlos
16-05-2024
0
0
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Among all types of DNA damage, DNA double-strand breaks (DSBs) are considered the most deleterious form induced by either endogenous factors (oxi-dative damages, mismatches, altered chromatin structures, and missing, or modified nucleotides) or exogenous factors, i.e., ultraviolet (UV) radiation, ionizing radiation (IR), and chemicals or drugs. This study aimed: To evaluate the effect of DNAPKi NU7441 on the HCT116 cell line.
11p
vijaychest
16-05-2024
2
1
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This study aims to analyze the simultaneous relationship between supply chain strategy and profitability. This study will also analyze the effect of capital structure and profitability on firm value based on the supply chain strategy. Furthermore, it will analyze the factors that influence capital structure, profitability and firm value in manufacturing companies in Indonesia.
13p
longtimenosee09
08-04-2024
2
0
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Part 2 book "Molecular biology of drug addiction" includes content: Influence of environmental and hormonal factors in sensitivity to psychostimulants; development and expression of behavioral sensitization - temporal profile of changes in gene expression; new advances in the identification and physiological roles of the components of the endogenous cannabinoid system; opioid system involvement in cannabinoid tolerance and dependence, genetic basis of ethanol reward,... and other contents.
215p
muasambanhan08
04-03-2024
1
1
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The deregulation of microRNA-140 (miRNA-140) has been reported to be involved in the human pathogenesis of Osteoarthritis (OA). However, in Vietnam, to our knowledge, there is a limited study of evaluation of a miRNA-140 expression. The commercial kits for the quantitation of miRNA-140 are more expensive.
7p
vibego
02-02-2024
1
0
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Recurrent episodes of hypoglycemia may be caused by several factors, including drugs, critical illnesses, hormonal defciency, non-islet cell tumor endogenous hyperinsulinism, and accidental, surreptitious, or malicious hypoglycemia. Multiple drugs have been previously reported as causes of hypoglycemia, with moderate and lowquality evidence.
4p
vitiki
30-01-2024
3
2
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Liver cirrhosis is a well-known risk factor for hepatocellular carcinoma (HCC). However, some HCC cases can also originate from non-cirrhotic livers. The aim of this study was to identify key circular RNAs (circRNAs) associated with the tumorigenesis of non-cirrhotic liver disease.
15p
vileonardodavinci
23-12-2023
7
5
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Cholesterol and lipids play an important role in sustaining tumor growth and metastasis in a large variety of cancers. ANGPTL3 and PCSK9 modify circulating cholesterol levels, thus availability of lipids to peripheral cells. Little is known on the role, if any, of circulating lipid-related factors such as PCSK9, ANGPTL3 and lipoprotein (a) in cancers.
12p
vialfrednobel
23-12-2023
4
3
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Melanoma differentiation-associated gene 7 (Mda-7) encodes IL-24, which can induce apoptosis in cancer cells. A novel gene therapy approach to treat deadly brain tumors, recombinant mda-7 adenovirus (Ad/ mda-7) efficiently kills glioma cells. In this study, we investigated the factors affecting cell survival and apoptosis and autophagy mechanisms that destroy glioma cells by Ad/IL-24.
13p
visharma
20-10-2023
7
2
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The objectives of this thesis are: To determine shareholder wealth effects in relation to the announcement of inclusion in a social index; to understand the determinants of the valuation effect due to inclusion in a social index; to investigate the mediating role of institutional investors; to address the endogeneity issue that is inherent in our study; to test whether CSR is a strategic engagement by firms to retain market value.
303p
runthenight04
02-02-2023
4
1
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High-risk human papillomavirus (HR-HPV) is the main aetiological factor for the development of cervical cancer. While nearly 70% of HR-HPV infections are cleared within 12 months, in the remainder of women they persist and can progress into cervical cancer.
6p
vipriyankagandhi
27-07-2022
3
1
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All mRNAs are bound in vivo by proteins to form mRNA–protein complexes (mRNPs), but changes in the composition of mRNPs during posttranscriptional regulation remain largely unexplored. Here, we have analyzed, on a transcriptome-wide scale, how microRNA-mediated repression modulates the associations of the core mRNP components eIF4E, eIF4G, and PABP and of the decay factor DDX6 in human cells.
18p
vialfrednobel
29-01-2022
8
0
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Spinach is a beneficial annual vegetable species and sensitive to the bolting or early flowering, which causes a large reduction in quality and productivity. Indeed, bolting is an event induced by the coordinated effects of various environmental factors and endogenous genetic components. Although some key flowering responsive genes have been identified in spinach, non-coding RNA molecules like long non-coding RNAs (lncRNAs) were not investigated yet.
23p
vilarryellison
29-10-2021
4
0
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Light is the main source of energy and, as such, is one of the most important environmental factors for plant growth, morphogenesis, and other physiological responses. MicroRNAs (miRNAs) are endogenous noncoding RNAs that contain 21–24 nucleotides (nt) and play important roles in plant growth and development as well as stress responses.
11p
vijeeni2711
24-07-2021
27
0
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Yam tuber is a storage organ, derived from the modified stem. Tuber expansion is a complex process, and depends on the expressions of genes that can be influenced by environmental and endogenous factors.
18p
vijeeni2711
24-07-2021
10
0
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Phytohormones are the key factors regulating vascular development in plants, and they are also involved in tension wood (TW) formation. Although the theory of hormone distribution in TW formation is widely supported, the effects of endogenous hormones on TW formation have not yet been assessed.
16p
vijeeni2711
30-06-2021
14
1
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Bolting refers to the early flowering stem production on agricultural and horticultural crops before harvesting. Indeed, bolting is an event induced by the coordinated effects of various environmental factors and endogenous genetic components, which cause a large reduction in the quality and productivity of vegetable crops like spinach.
18p
vijichea2711
28-05-2021
13
1
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Grape buds and leaves are directly associated with the physiology and metabolic activities of the plant, which is monitored by epigenetic modifications induced by environment and endogenous factors.
16p
vijichea2711
28-05-2021
10
1
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Over the life cycle of perennial trees, the dormant state enables the avoidance of abiotic stress conditions. The growth cycle can be partitioned into induction, maintenance and release and is controlled by complex interactions between many endogenous and environmental factors.
18p
vijichea2711
28-05-2021
10
2
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