Enrichment peaks

In paper "Strain based brittle failure criteria for rocks" the enriched extension strain criterion is proposed as a threshold surface for crack initiation CI and crack damage CD and as a failure surface at peak P. Examples show that the enriched extension strain criterion predicts much lower volumes of damaged rock mass compared to the simple extension strain criterion.

10p dathienlang1012 03-05-2024 1 0   Download

Chromatin immunoprecipitation combined with high-throughput sequencing (ChIP-Seq) is the most frequently used method to identify the binding sites of transcription factors. Active binding sites can be seen as peaks in enrichment profiles when the sequencing reads are mapped to a reference genome.

11p viwyoming2711 16-12-2020 11 1   Download

Genome-wide tiling array experiments are increasingly used for the analysis of DNA methylation. Because DNA methylation patterns are tissue and cell type specific, the detection of differentially methylated regions (DMRs) with small effect size is a necessary feature of tiling microarray ‘peak’ finding algorithms, as cellular heterogeneity within a studied tissue may lead to a dilution of the phenotypically relevant effects.

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Correctly identifying genomic regions enriched with histone modifications and transcription factors is key to understanding their regulatory and developmental roles. Conceptually, these regions are divided into two categories, narrow peaks and broad domains, and different algorithms are used to identify each one.

10p vioklahoma2711 19-11-2020 9 2   Download

ChIP-seq experiments are widely used to detect and study DNA-protein interactions, such as transcription factor binding and chromatin modifications. However, downstream analysis of ChIP-seq data is currently restricted to the evaluation of signal intensity and the detection of enriched regions (peaks) in the genome.

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Tracing stable isotopes, such as 13C using various mass spectrometry (MS) methods provides a valuable information necessary for the study of biochemical processes in cells. However, extracting such information requires special care, such as a correction for naturally occurring isotopes, or overlapping mass spectra of various components of the cell culture medium.

9p vioklahoma2711 19-11-2020 1 1   Download

The application of high-throughput sequencing in a broad range of quantitative genomic assays (e.g., DNA-seq, ChIP-seq) has created a high demand for the analysis of large-scale read-count data. Typically, the genome is divided into tiling windows and windowed read-count data is generated for the entire genome from which genomic signals are detected (e.g. copy number changes in DNA-seq, enrichment peaks in ChIP-seq).

11p viconnecticut2711 28-10-2020 10 0   Download

An incubation experiment was conducted at ADAC & RI, Trichy, to study the effect of ZnSO4, chelated Zn and Zn enriched organics on dynamics of Zn in sodic soil at different incubation period. The organics viz., FYM, press mud, poultry manure and vermicompost were enriched (10:1 ratio) with ZnSO4 @ 37.5 kg ha-1 (recommended dose for hybrid maize). The ZnSO4, chelated Zn and Zn enriched organics were added @ 37.5 kg ZnSO4 ha-1 . Incubated soil sample were analysed for Zn fractions viz.

7p nguaconbaynhay1 04-12-2019 12 0   Download

To describe the X-ray peaks, a Lorentzian broadened shape function was used, and methods were developed to reduce the number of fitting parameters for decomposing the strongly overlapping peaks using channel-energy, energy-width, and energy-efficiency calibration functions

7p minhxaminhyeu5 30-06-2019 24 1   Download