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Environmental risk factor
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Results regarding whether it is essential to incorporate genetic variants into risk prediction models for esophageal cancer (EC) are inconsistent due to the different genetic backgrounds of the populations studied. We aimed to identify single-nucleotide polymorphisms (SNPs) associated with EC among the Chinese population and to evaluate the performance of genetic and non-genetic factors in a risk model for developing EC.
10p
vishanshan
27-06-2024
2
1
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This study is designed to explore the potential impact of individual and environmental residential factors as risk determinants for bone and soft tissue cancers, with a particular focus on the Indonesian context.
13p
vikoch
27-06-2024
2
1
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Robustness of supply chain is rapidly expanding due to mitigation and reduction in the risk of unexpected and destructive events in the companies. As it is impossible for companies to resume their business post major crisis, the prediction of environmental factors that surround the companies paved way for development of a disaster recovery plan. 80% of the companies suffer from business interruptions and lack clarity in disaster management plan.
7p
longtimenosee10
26-04-2024
3
1
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Vietnam is often viewed as one of the most vulnerable countries to climate change. As the result of environmental risks coming along with climate changes, Vietnam economy are now facing the problem of increased stranded asset risks caused by climate change. In this study we analyzed the causes of stranded assets. Focusing on analyzing the power industry, the article also points out factors affecting stranded assets in the power industry. Studying the case of Quang Trach thermal power plant, the article shows risks to assets of thermal power companies in Vietnam in the future.
12p
longtimenosee09
08-04-2024
5
3
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The etiology of ASD involves both inherited and environmental risk factors, with epigenetic processes hypothesized as one mechanism by which both genetic and non-genetic variation influence gene regulation and pathogenesis. The aim of this study was to identify DNA methylation biomarkers of ASD detectable at birth.
13p
vibransone
28-03-2024
3
2
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Endometrial cancer studies have led to a number of well-defined but mechanistically unconnected genetic and environmental risk factors. One of the emerging modulators between environmental triggers and genetic expression is the microbiome. We set out to inquire about the composition of the uterine microbiome and its putative role in endometrial cancer.
15p
vioraclene
31-03-2024
2
1
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Age-related macular degeneration (AMD) is a common condition of vision loss with disease development strongly influenced by environmental and genetic factors. Recently, 34 loci were associated with AMD at genome-wide significance. So far, little is known about a genetic overlap between AMD and other complex diseases or disease-relevant traits.
13p
vioraclene
31-03-2024
7
2
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Genome-wide association studies (GWASs) have identified thousands of variants associated with asthma and other complex diseases. However, the functional effects of most of these variants are unknown. Moreover, GWASs do not provide context-specific information on cell types or environmental factors that affect specific disease risks and outcomes.
22p
vibransone
28-03-2024
6
2
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Type 2 diabetes (T2D) is a worldwide scourge caused by both genetic and environmental risk factors that disproportionately afflicts communities of color. Leveraging existing large-scale genome-wide association studies (GWAS), polygenic risk scores (PRS) have shown promise to complement established clinical risk factors and intervention paradigms, and improve early diagnosis and prevention of T2D.
16p
viellison
28-03-2024
7
2
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In this study, we dissect the subcutaneous adipose tissue (SAT) methylome signature relevant to metabolic health by focusing on VF as the major risk factor of metabolic disease. We integrate results with genetic, blood methylation, SAT gene expression, blood metabo‑ lomic, dietary intake and metabolic phenotype data to assess and quantify genetic and environmental drivers of the identified signals, as well as their potential functional roles.
22p
viellison
28-03-2024
4
2
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Air pollution is one of the leading risk factors for death but also a significant contributor to the global disease burden, affecting quality of life. According to a World Health Organisation (WHO) report, seven million people die from air pollution every year, and 9 out of 10 people worldwide breathe polluted air. Any person can be affected by exposure to polluted air, especially the elderly, children, pregnant women, and people with comorbidities.
9p
viellison
28-03-2024
2
1
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Hearing problems (HP) in adults are common and are associated with several comorbid conditions. Its prevalence increases with age, reflecting the cumulative effect of environmental factors and genetic predisposition. Although several risk loci have been already identified, HP biology and epidemiology are still insufciently investigated by large-scale genetic studies.
18p
vicwell
29-02-2024
3
1
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Metabolic pathways are related to physiological functions and disease states and are influenced by genetic variation and environmental factors. Hispanics/Latino individuals have ancestry-derived genomic regions (local ancestry) from their recent admixture that have been less characterized for associations with metabolite abundance and disease risk.
13p
vicwell
29-02-2024
5
1
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Changes in cell-type composition of tissues are associated with a wide range of diseases and environmental risk factors and may be causally implicated in disease development and progression. However, these shifts in cell-type fractions are often of a low magnitude, or involve similar cell subtypes, making their reliable identification challenging.
24p
vicwell
29-02-2024
3
1
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The relative contributions of genetic and environmental factors versus unavoidable stochastic risk factors to the variation in cancer risk among tissues have become a widely-discussed topic. Some claim that the stochastic effects of DNA replication are mainly responsible, others believe that cancer risk is heavily affected by environmental and hereditary factors.
12p
vileonardodavinci
23-12-2023
4
4
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Ebook "Corporate governance and contingency theory: A structural equation modeling approach and accounting risk implications" analyzes the determinants and effectiveness of corporate governance in an integrated model drawing on contingency theory and employing structural equation modeling (SEM). Business competition as an environmental factor and strategy as an organizational factor are important determinants of corporate governance, while organizational performance and earnings quality are two dimensions of its effectiveness.
188p
tuongnhuoclan
28-11-2023
6
2
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In the context of industrialization and modernization, environmental pollution is not a new phenomenon, but still remains the world’s greatest problem. At the same time, green consumption plays an increasingly important role in protecting environment. The study finds out the factors that affect the green consumption behavior of Vietnamese Generation Z by conducting a survey in March, 2021.
14p
viindra
06-09-2023
6
3
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Birth month and climate impact lifetime disease risk, while the underlying exposures remain largely elusive. We seek to uncover distal risk factors underlying these relationships by probing the relationship between global exposure variance and disease risk variance by birth season.
14p
visteverogers
24-06-2023
6
2
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Synchronous or metachronous multiple primary malignancies (MPMs) are a known phenomenon. These occurrences may be spontaneous or related to environmental risk factors or genetic predisposition. Chronic myelogenous leukemia (CML) and Multiple myeloma (MM) are two uncommon hematologic malignancies, arises from two different cell lineage.
6p
videadpool
05-05-2023
6
2
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Genome-wide association studies have identified numerous single nucleotide polymorphisms (SNPs) as associated with colorectal cancer (CRC) risk in populations of European descent. However, their utility for predicting risk to CRC in Asians remains unknown.
7p
vinarcissa
21-03-2023
7
2
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