Febrile illness
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Fusobacterium nucleatum is an anaerobic bacterium mainly responsible for acute or chronic infection of the ear, nose, and throat, potentially bacteremic with a risk of extraoral metastatic infection.
6p vilazada 31-01-2024 4 2 Download
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Acute disseminated encephalomyelitis is a well-known, but rare, side effect of some vaccines, or symptom following a febrile illness. In this case, we highlight the need for a regulatory framework to assist clinicians and patients with coverage of treatment for acute disseminated encephalomyelitis.
5p vitiki 30-01-2024 9 2 Download
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There could be misdiagnosis of coronavirus disease 2019 for malaria and vice versa because of their similar presentations, particularly when clinicians rely mainly on symptoms for diagnosis. Coinfection with coronavirus disease 2019 and malaria is associated with increased all-cause in-hospital mortality compared with isolated infection with severe acute respiratory syndrome coronavirus 2.
5p vitiki 30-01-2024 10 2 Download
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Coxiella burnetii is a zoonotic pathogen that resides in wild and domesticated animals across the globe and causes a febrile illness, Q fever, in humans. An improved understanding of the genetic diversity of C. burnetii is essential for the development of diagnostics, vaccines and therapeutics, but genotyping data is lacking from many parts of the world.
17p visilicon2711 20-08-2021 9 1 Download
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The present study was mainly focussed to determine the bacterial agents causing febrile illnesses in children between 1 month to 12 years of age, and their antimicrobial susceptibility pattern and also to find out the distribution of different bacterial isolates among the study population.
14p chauchaungayxua10 19-03-2021 14 4 Download
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Dengue is a mosquito-borne viral disease affecting tropical and subtropical regions of the world. Symptoms may range from a mild undifferentiated febrile illness to dengue fever (DF) and dengue haemorrhagic fever (DHF), a potentially life threatening disease. Detection of non-structural antigen (NS1 Ag) may help in the early diagnosis and treatment of dengue. Aim of the study is to detect dengue infection by NS1 Ag detection and also to know its prevalence.
5p gaocaolon9 22-12-2020 9 1 Download
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China-Burma-India field party of the United States of America Typhus Commission has reported their observations on scrub typhus in Assam and Burma in 1946. Recently, sporadic cases have been reported from areas of Assam covered with scrub forests. Here we report few cases of scrub typhus presented with acute febrile illness associated with typical skin lesion of scrub typhus.
5p nguathienthan8 20-10-2020 7 1 Download
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Fever has become a common presenting complaint in the developing world. The symptoms and differential diagnosis of the most common fevers in the tropics that making an accurate clinical diagnosis was difficult without laboratory confirmation. These fevers also lead to high morbidity and mortality. But the exact burden of each infection varies from region to region. Due to high prevalence of local individual diseases the prioritization of the differential diagnosis of a clinical syndrome of acute undifferentiated febrile illness (AUFI) was needed.
9p trinhthamhodang7 31-08-2020 6 1 Download
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Scrub typhus (ST) is an acute febrile illness caused by Orientia tsutsugamushi, and is associated with considerable morbidity and mortality. ST has been considered as one of the most emerging infections in India as shown by the increase in the number of clinically diagnosed patients in various states except Uttar Pradesh. The present study was undertaken to look for ST amongst patients presenting with suggestive pyrexia of unknown origin (PUO) at a tertiary care centre in Uttar Pradesh.
10p trinhthamhodang6 09-07-2020 17 1 Download
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Leptospirosis is zoonosis, presenting as a febrile illness with protean manifestations. Since disease is amenable to antibiotic therapy, early diagnosis helps in better management and prevention of complications. In many parts of our country, prevalence is either underestimated or unestimated. Hence this study was conducted with the objective of determining the seroprevalence of leptospirosis among clinically suspected cases, describe the various sociodemographic parameters, occupation and risk factors among seropositive cases.
8p chauchaungayxua6 26-06-2020 13 2 Download
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Objective of the study is to determine seroprevalence of dengue infection in patients suffering from AFI, seroprevalence of susceptible population and to ascertain whether it is appropriate time to introduce dengue vaccine CYD-TDV to susceptible population. A retrospective cross sectional observational study, of records of all patients of AFI, whose sera was subjected to simultaneous detection of dengue NS1 antigen, antidengue IgM and IgG antibody was done from July 2016 to July 2017 at a tertiary care center in eastern India
7p chauchaungayxua5 05-05-2020 6 1 Download
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Scrub typhus is one of the most under-diagnosed and under-reported febrile illnesses. Hence, a study was conducted to diagnose the scrub typhus by using Weil Felix test (WF), Immuno-Chromatographic Test (ICT) and nested PCR (N-PCR). The primer pairs encoding the 56-KDa antigen were used for confirmation of Orientia tsutsugamushi. Serotype-specific primers were used for identification of Gilliam, Karp, Kato, Kawasaki and Kuroki strains. Out of the 46 blood samples collected from suspected human patients, 13 were found serologically positive by both WF and ICT and 12 by N-PCR.
8p angicungduoc4 26-04-2020 14 0 Download
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Gloriosa superba (GSb) is a highly poisonous plant and its toxicity is due to anti-mitotic effects of constituents such as colchicine and gloriosine on rapidly proliferating cells. Poisoning is known to cause very rapid and severe clinical manifestations due gastro intestinal, neurological, cardiac and bone marrow toxicity.
4p vienzym2711 30-03-2020 15 1 Download
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Rickettsial disease is one among the most common re-emerging disease and untreated cases having fatality rates as high as 30-35% and since it is a cause of fever of unknown origin(FUO) it needs to be differentiated from other febrile illnesses. The present study was performed at a tertiary care Centre in Bangalore after taking Ethical Clearance from the Institution’s Ethical Committee. All 101 Paediatric patients admitted in the Paediatric department of M. S. Ramaiah Hospitals were included in the study in the year 2015. The study revealed 5.
6p caygaocaolon2 14-03-2020 11 1 Download
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An estimated one-third of children younger than 5 years in low- and middle-income countries fail to meet their full developmental potential. The first year of life is a period of critical brain development and is also when most of the morbidity from infection is suffered.
9p vinatri2711 29-02-2020 12 1 Download
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Exposure of red blood cells to oxidants increases production of methemoglobin (MHb) resulting in impaired oxygen delivery to tissues. There are no reliable estimates of methemoglobinemia in low resource clinical settings.
12p videshiki2711 21-02-2020 12 1 Download
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Glycosylation patterns of serum proteins, such as α1-acid glycoprotein, are modified during an acute phase reaction. The response of acute Kawasaki disease (KD) patients to IVIG treatment has been linked to sialic acid levels on native IgG, suggesting that protein glycosylation patterns vary during the immune response in acute KD.
11p videshiki2711 21-02-2020 38 1 Download
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Dengue fever is a re-emerging viral disease commonly occurring in tropical and subtropical areas. The clinical features and abnormal laboratory test results of dengue infection are similar to those of other febrile illnesses; hence, its accurate and timely diagnosis for providing appropriate treatment is difficult.
9p vidr2711 19-02-2020 13 1 Download
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Health care providers lacking proper diagnostic tools are usually unable to determine specific etiologies, often diagnosing patients with acute undifferentiated febrile illness (AUFI) presumptively based on clinical features and assumptions regarding circulating pathogens. Acute fever can be potentially fatal if the etiology is not recognized and treated appropriately. A cross-sectional study was conducted in a tertiary care hospital, Bengaluru, from July-December 2018. Blood was collected from patients with acute fever for peripheral smear, serological tests.
7p trinhthamhodang3 12-02-2020 13 0 Download
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Rickettsial diseases are an important cause of undifferentiated acute febrile illness. The lack of classical manifestations can make their diagnosis difficult. Even though the diseases are endemic in India, they are less reported from New Delhi and surrounding regions. Aim is to estimate the seropositivity of Rickettsial infections in cases of undifferentiated acute febrile illness from a tertiary care hospital in New Delhi and to analyze their clinical profile. This prospective observational study was conducted from November 2016 to March 2018.
9p kequaidan2 11-12-2019 23 0 Download