Gait decline

Levodopa therapy is the standard pharmacological treatment for Parkinson’s disease (PD). However, after an initial period of significant benefit, the effects of levodopa begin to wear off. This results in a reduction in the effect duration and the development of motor complications.

5p viwhitewolf 03-07-2023 4 2   Download

Dual-task gait performance declines as humans age, leading to increased fall risk among older adults. It is unclear whether different secondary cognitive tasks mediate age-related decline in dual-task gait. This study aimed to examine how type and difficulty level of the secondary cognitive tasks differentially affect dual-task gait in older adults.

12p vinobelprisen 26-03-2022 10 4   Download

Although the studies differ in population coverage, sample design, method and periodicity of measurement, use of proxies, and treatment of nonresponse and missing data, the authors conclude that most analyses using data from the post- 1980 period show declines in the percentage with moderate disability and IADL disability. These declines have been shown to vary by gender (18, 47) and level of education (18); and they also differ between the young-old and the old-old (19). Generally, there is more improvement in less-severe disability....

7p thankinhphanliet 01-01-2013 54 3   Download

Disorders of Gait The heterogeneity of gait disorders observed in clinical practice reflects the large network of neural systems involved in the task. There is the potential for abnormalities to develop, and walking is vulnerable to neurologic disease at every level. Gait disorders have been classified descriptively, based on the abnormal physiology and biomechanics. One problem with this approach is that many failing gaits look fundamentally similar. This overlap reflects common patterns of adaptation to threatened balance stability and declining performance.

5p ongxaemnumber1 29-11-2010 63 2   Download